amphetamines) until it has been determined whether the tics val • Coadministration with drugs that inhibit CYP3A enzymes marrow depression • Narrow-angle glaucoma • Clients with CNS-depressed clients • Clients with blood dyscrasias or bone Action● • Parkinson disease (are caused by the medications or Tourette’s disorder (● liver, renal, or cardiac insuffidrugs that may cause tics (e.g., pemoline, methylphenidate, To u r e t t e ’s d i s o r d e r ((• Coadministration with other drugs that prolong the QT inter-Contraindications and Precautions Contraindicated in:^478 pimozideDemonstrates varying affilimbic system, and reticular formation Blocks postsynaptic dopamine receptors in the hypothalamus, and histaminic receptors^ ●^ PSYCHOTROPIC MEDICATIONS) • Treatment of tics other than those associated with pimozidehaloperidol • Hypersensitivity to the drug nity for cholinergic, alpha ciency • Pregnancy and lactation ) • Coadministration with other ) • In comatose or severely^1 -adrenergic, pimozide)
2506_Ch28_472-501.indd 1478 2506 Ch 28 472 - 501 .ind(• Children • Elderly patients with dementia-related psychosis Use Cautiously in:(● • Clients with respiratory insuffiAdverse Reactions and Side Effects● ● ● ● ● ● ● ● ● ● ● clients • Depressed clients • Clients with history of seizures dPimozide(Trade) Generic Name safety not establishedblack box warning Constipation Sedation Orthostatic hypotension Urinary retention Photosensitivity Blurred vision Decreased libido Nausea Amenorrhea Dry mouth Retrograde ejaculation Skin rash 1 (Orap) 478 Half-life Pregnancy Categories/C/~55 hr) ) • Elderly and debilitated clients • Diabetic ●Unlabeled uses:●Indications^ Touret te’s disorder Schizophrenia ciency • Prostatic hypertrophy Tabs: 1, 2 Available Forms (mg) 1 10/1/10 9:40:06 AM 0 / 1 / 10 9 : 40 : 06 AM
