Saylor URL: http://www.saylor.org/books Saylor.org
Mechanism Symptoms Drug
Dangers and side
effects
Psychological
dependence
Physical
dependence
Addiction
potential
Addiction
potential
or chewed
Cocaine
Decreased
appetite, headache Low Low Moderate
Amphetamines
Possible
dependence,
accompanied by
severe “crash”
with depression as
drug effects wear
off, particularly if
smoked or injected Moderate Low
Moderate
to high
Depressants
Depressants change
consciousness by
increasing the
production of the
neurotransmitter GABA
and decreasing the
production of the
neurotransmitter
acetylcholine, usually at
the level of the thalamus
and the reticular
formation.
Calming effects,
sleep, pain relief,
slowed heart rate
and respiration
Alcohol
Impaired
judgment, loss of
coordination,
dizziness, nausea,
and eventually a
loss of
consciousness Moderate Moderate Moderate
Barbiturates and
benzodiazepines
Sluggishness,
slowed speech,
drowsiness, in
severe cases, coma
or death Moderate Moderate Moderate
Toxic inhalants
Brain damage and
death High High High
Opioids
The chemical makeup of
opioids is similar to the
endorphins, the
neurotransmitters that
serve as the body’s
“natural pain reducers.”
Slowing of many
body functions,
constipation,
respiratory and
cardiac
depression, and
the rapid
development of
tolerance
Opium
Side effects
include nausea,
vomiting,
tolerance, and
addiction. Moderate Moderate Moderate
Morphine
Restlessness,
irritability,
headache and body
aches, tremors, High Moderate Moderate