WOMEN’S MEDICINE CRISES
390 Obstetric and Gynaecological Emergencies
2 Post-coital ‘morning after’ pill
This may be used up to 72 h after unprotected intercourse. Taking the dose as
soon as possible increases the efficacy.
(i) Give levonorgestrel 1.5 mg as a single dose
(a) do not prescribe in women with undiagnosed vaginal
bleeding, breast cancer or severe liver disease
(b) give 2.25 mg levonorgestrel (1.5 mg taken immediately and
750 g taken 12 hours later) in patients taking enzyme-
inducing drugs such as carbamazepine, rifampicin, phenytoin
and phenobarbitone (phenobarbital).
(ii) Give a repeat levonorgestrel dose if vomiting occurs within 2
hours, with an antiemetic such as metoclopramide 10–20 mg i.v.
or domperidone 20 mg orally.
(iii) Explain to the patient that:
(a) her next period may be early or late
(b) a barrier method of contraception must be used until her
next period
(c) there is an increased risk of ectopic pregnancy so she should
seek medical advice immediately if abdominal pain occurs.
(iv) Refer all patients for follow-up to their general practitioner (GP)
or a family planning clinic to check that:
(a) the pregnancy test is negative 3–4 weeks later
(b) there is no ectopic pregnancy
(c) the patient receives proper contraceptive advice for the
future.
Missed oral contraceptive pill
Usually a frantic call on the telephone requests advice on what to do following a
missed oral contraceptive pill. The critical time for loss of contraceptive protec-
tion is at the beginning or end of the menstrual cycle, due to extension of the
‘pill-free’ interval.
1 Combined oral contraceptive pill
(i) Up to 12 hours late: Take the missed pill and carry on as usual.
(ii) Over 12 hours late:
(a) continue normal pill taking, but for the next 7 days either
abstain from sex or use an alternative barrier method of
contraception such as the condom
(b) start the next packet immediately the present one is over,
if these 7 days run beyond the end of the packet; i.e. no gap
between packets
- this will mean that no period may occur until the end of two
packets
(c) miss out the seven inactive pills if the everyday pills are the
ones being taken