434 8 Food Additives
Fig. 8.4.Model of a sweetness receptor according toNofreandTinti(1996).a)Possible interactions of a sweet
substance with the receptor. Interactions of the receptor withb)glucose,c)sucrose andd)lugduname
is 0–2.5mg/kg of body weight. The synthesis
of saccharin usually starts with toluene (Rem-
sen/Fahlbergprocess, Formula 8.4) or sometimes
with the methyl ester of anthranilic acid (Maumee
process, Formula 8.5).
8.8.3 Cyclamate
Cyclamate is a widespread sweetener and is mar-
keted as the Na- or Ca-salt of cyclohexane sul-
famic acid. The sweetening strength is substan-