MicroBiology-Draft/Sample

(Steven Felgate) #1

Figure 3.53 Three variations of endocytosis are shown. (a) In phagocytosis, the cell membrane surrounds the
particle and pinches off to form an intracellular vacuole. (b) In pinocytosis, the cell membrane surrounds a small
volume of fluid and pinches off, forming a vesicle. (c) In receptor-mediated endocytosis, the uptake of substances is
targeted to a specific substance (a ligand) that binds at the receptor on the external cell membrane.


The process by which secretory vesicles release their contents to the cell’s exterior is calledexocytosis(Figure
3.41). Vesicles move toward the plasma membrane and then meld with the membrane, ejecting their contents out of
the cell. Exocytosis is used by cells to remove waste products and may also be used to release chemical signals that
can be taken up by other cells.


Cell Wall


In addition to a plasma membrane, some eukaryotic cells have a cell wall. Cells of fungi, algae, plants, and even
some protists have cell walls. Depending upon the type of eukaryotic cell, cell walls can be made of a wide range of
materials, including cellulose (fungi and plants); biogenic silica, calcium carbonate, agar, and carrageenan (protists
and algae); or chitin (fungi). In general, all cell walls provide structural stability for the cell and protection from
environmental stresses such as desiccation, changes in osmotic pressure, and traumatic injury.[29]


Extracellular Matrix


Cells of animals and some protozoans do not have cell walls to help maintain shape and provide structural stability.
Instead, these types of eukaryotic cells produce anextracellular matrixfor this purpose. They secrete a sticky
mass of carbohydrates and proteins into the spaces between adjacent cells (Figure 3.54). Some protein components
assemble into a basement membrane to which the remaining extracellular matrix components adhere. Proteoglycans
typically form the bulky mass of the extracellular matrix while fibrous proteins, like collagen, provide strength. Both
proteoglycans and collagen are attached to fibronectin proteins, which, in turn, are attached to integrin proteins. These
integrin proteins interact with transmembrane proteins in the plasma membranes of eukaryotic cells that lack cell
walls.


In animal cells, the extracellular matrix allows cells within tissues to withstand external stresses and transmits signals
from the outside of the cell to the inside. The amount of extracellular matrix is quite extensive in various types of



  1. M. Dudzick. “Protists.” OpenStax CNX. November 27, 2013. http://cnx.org/contents/f7048bb6-e462-459b-805c-ef291cf7049c@1


Chapter 3 | The Cell 129

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