Pharmacology for Anaesthesia and Intensive Care

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Section IIICardiovascular drugs

HO

HO

HO

Phenylephrine

Isoprenaline

Methoxamine

Dobutamine

Dopexamine

Ephedrine

Metaraminol Salbutamol

HO

HO

HO

OH

HO

C CH 2 N

H H

OH

CH 3

C

H

OH

C

H

N

NN

H

H

C

OH

HO HO N

H

HOH 2 C

CN

HH

H

H

C

H

OH

OH

CC

HH

(CH 2 ) 2

(CH 2 ) 2

(CH 2 ) 2

C(CH 3 ) 3

(CH 2 ) 6 (CH 2 ) 2

CH 3

NH 2

CH 3

H

C

OH

C

H

CH 3

C

CH 3

NH 2

CH 3

CH 3 O

CH 3 O

CH 3

CH 2

CH 2

CH 3

H

H

N

Figure 12.4.Structure of some synthetic sympathomimetic amines.