Pediatric Nutrition in Practice

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eficial effect of EAABF was reported in an open
case study involving only 4 SBS patients with per-
sistent feeding intolerance [13]. A retrospective
study found a shorter duration of PN dependency
with the use of EAABF [14]. Current data are in-
sufficient to recommend such expensive formu-
las with often increased osmolality for infants
and children with SBS.


Glutamine (Gln) , a nonessential amino acid,
plays an important role in energy metabolism of
the intestinal mucosa and other rapid-turnover
tissues. A randomized controlled pilot study of
Gln-supplemented EF in infants with IF failed to
show any advantages [15]. Gln cannot be recom-
mende d u n le s s la rger mu lt ic enter t r ia l s on i n fa nt s
with IF provide evidence for beneficial effects.

Ta b l e 4. Different routes of feeding


Devices Indications Contraindications Advantages Disadvantages or risks


OF
None To be used
systematically


Artificial ventilation
Orofacial
malformation

Discontinuous physiologic
mode of feeding
Self-regulation of intake
EGF release by salivary
glands
Promotes bowel
adaptation
Psychological behavior

Insufficient intake

Gastric feeding
Nasogastric Nutritional support
<3 months


Severe GE reflux
Slow gastric emptying

Easy to place even at home Frequent dislodgements
Nasal symptoms

Percutaneous
endoscopic
gastrostomy


Nutritional support
>3 months

Repeated abdominal
surgery
Abnormal gastric
anatomy

Fewer occlusions with
larger bore, one-step low-
profile devices available

Skin injury at abdominal
exit site

Surgical
gastrostomy


Nutritional support
>3 months

Poor candidate for
surgery

Immediate placement of
low-profile device, direct
visualization of stomach

Open surgery

Duodenal or jejunal feeding
Nasojejunal Short term for
patients with severe
GERD, gastric
dysmotility


Recent proximal
surgical anastomosis

Radiologic or bedside
placement techniques
Noninvasive

Frequent dislodgements
Risk of intussusception
Nasal symptoms
Intestinal contamination

Gastrojejunal Longer-term EF for
patients with severe
GERD, gastric
dysmotility or need
for gastric
decompression


Recent proximal
surgical anastomosis

Endoscopic or radiologic
placement through
existing gastrostomy tube

Requires healing of
gastrostomy tract prior to
placement
Skin injury at abdominal
exit site
Frequent occlusions of
jejunal port
Intestinal contamination

Jejunal Long-term EF for
patients with severe
GERD and upper
intestinal dysmotility


Dysmotility Direct surgical access to
small intestine

Open surgical procedure
Mechanical problems
Intestinal contamination

GE = Gastroesophageal; GERD = gastroesophageal reflux disease.


Koletzko B, et al. (eds): Pediatric Nutrition in Practice. World Rev Nutr Diet. Basel, Karger, 2015, vol 113, pp 182–189
DOI: 10.1159/000360339
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