Signs and Symptoms
Irritability
Poor appetite
Mild growth delay
Tires easily
Changes in gait
Poor weight gain
High fever
Rash
Flex position at rest
Test Results
Increased erythrocyte sedimentation rate (ESR)
Positive rheumatoid factor (RF) in serum
Positive immunoglobulin (Ig)G and IgM present in serum
Positive antinuclear antibodies (ANA) in serum
Low hemoglobin
Treatments
Administer nonsteroidal antiinflammatory drugs (NSAIDs) such as
ibuprofen and naproxen for pain relief. It can take 3 weeks for antiin-
flammatory response to occur.
Administer slow-acting antirheumatic drugs (SAARDS) such as
methotrexate, sulfasalazine, and hydroxychloroquine to suppress the
autoimmune response.
Administer steroids if other treatments fail. Steroids reduce inflamma-
tion but have adverse side effects with long-term use.
Administer etanercept (Enbrel) if NSAIDs and SAARDS fail. Etanercept
blocks the binding of tumor necrosis factor with cell surface receptors,
thus reducing inflammation.
Physical therapy to ensure safety ambulation.
Nursing alert Monitor the patient for signs of infection because antiinflamma-
tory medication suppresses the immune system.
Nursing Interventions
Perform range-of-motion exercise on the affected joint to maintain joint
mobilization.
Encourage nonweight bearing activities to strengthen muscles.
Use splints and braces to reduce flexion and minimize pain.
Monitor renal and hepatic labs to detect adverse reaction to long use of
NSAIDs.
Apply warm compresses on joints when sleeping to prevent viscous that
results in stiffness.
CHAPTER 13/ Musculoskeletal Conditions^293