Science - USA (2021-11-12)

(Antfer) #1

a between-subjects factor. Next, syntactic per-
formance was analyzed through a LMM on
RTs withTraining(tool use versus free hand
versus video in Experiment 2 and tool use
versus free hand versus constrained hand in
Experiment 3) as the between-subjects fac-
tor andSentence(coordinated clauses versus
subject-relative clauses versus object-relative
clauses) andTime(pretest versus posttest) as
within-subjects factors.Subjects,Sentence, and
Timewere added to account for random effects.
rmANOVA was run ond′, withTraining(tool
use versus free hand versus video in Experi-
ment 2 and tool use versus free hand versus
constrained hand in Experiment 3) as the
between-subjects factor andSentence(coor-
dinated clauses versus subject-relative clauses
versus object-relative clauses) andTime(pre-
test versus posttest) as within-subjects factors.
To quantify the robustness of the syntactic
benefits after tool-use training across Experi-
ments 2 and 3, we finally computed the effect
size of the pretest-to-posttest improvement in
the syntactic task ( 41 , 43 ). This was done by
calculating the difference between pretest and
posttest performance divided by the pooled
SD in the pretest (for the entire sample of
participants). The effect size in the object rela-
tive clauses condition was then analyzed in an
rmANOVA withTraining(tool use versus free
hand) andExperiment(Experiment 2 versus
Experiment 3) as between-subjects factors.


Experiments 4 and 5: Statistics


In Experiment 4, to assess the progress in
performance during syntactic training, an
rmANOVA ond′and an LMM on RTs were
conducted. The rmANOVA was performed
withBlock(six blocks) as the within-subjects
factor andTraining(object-relative clauses
versus subject-relative clauses) as the between-
subjects factor. The LMM performed on RTs
included the same within-subject factor, with
SubjectsandBlockas random factors.
Next, motor performance with the tool was
analyzed through an LMM on the total num-
ber of inserted pegs withTraining(object-
relative clauses versus subject-relative clauses)
as the between-subjects factor andTime(pre-
test versus posttest) andBlock(four blocks) as
within-subjects factors.Subjects,Time, andBlock
were added to account for random effects.
Finally, to corroborate our results, motor per-
formance was analyzed using an rmANOVA
on the individual improvement slope (b) with
Training(object-relative clauses versus subject-
relative clauses) as the between-subjects fac-
tor andTime(pretest versus posttest) as the
within-subjects factor. Improvement slope was
obtained by performing a linear regression over
the number of inserted pegs for each partici-
pant before and after syntactic training sep-
arately. Slopes were also compared against
zero with one-samplettests for object relatives


and subject relatives separately. No difference
against zero predicted no improvement (i.e.,
flat slope), whereas a significant difference pre-
dicted a change in performance, as indexed
by a positive (i.e., increased performance) or
negative (i.e., decreased performance) slope.
Bonferroni correction was applied to correct
Pvalues for multiple comparisons.
In Experiment 5, similar models to Experi-
ment 4 were applied. To assess the progress
in performance during syntactic training, we
conducted an rmANOVA ond′and an LMM
on RTs. The rmANOVA was performed with
Block(six blocks) as the within-subjects fac-
tor andMotor Test(tool versus constrained
hand) as the between-subjects factor. The
LMM performed on RTs included the same
within-subject factor, withSubjectsandBlock
as random factors. To evaluate motor per-
formance, an rmANOVA was performed on
the number of pegs inserted in pretest and
posttest. For pretest, we considered the num-
ber of pegs inserted in the last block, namely
when the participants reached the required
motor threshold (eight pegs). Conversely, for
posttest, we calculated the mean across the
four blocks performed. The rmANOVA was
performed withTime(pretest versus post-
test) as the within-subjects factor andMotor
Test(tool versus constrained hand) as the
between-subjects factor. An rmANOVA was
also conducted by considering only the post-
test performance across the four blocks per-
formed. The rmANOVA includedBlock(four
blocks) as the within-subjects factor andMotor
Test(tool versus constrained hand) as the
between-subjects factor. To corroborate the
effects found in the Experiment 4, paired-
samplettests were performed between the
last pretest block (i.e., when the threshold
was reached) and each of the posttest blocks
separately for the tool-use and constrained-
hand conditions. Two-samplettests were
additionally conducted to compare the number
of pegs inserted between the two motor con-
ditions for each posttest block. Bonferroni
correction was applied to account for multiple
comparisons. As in Experiment 4, we ana-
lyzed the improvement slope (b). This was
obtained by performing a linear regression
over the number of inserted pegs for each par-
ticipant after syntactic training. Slopes were
also compared against zero with one-sample
ttests for tool use and constrained hand sepa-
rately. Bonferroni’s correction was applied to
correctPvalues for multiple comparisons.

REFERENCESANDNOTES


  1. L. E. Milleret al., Sensing with tools extends somatosensory
    processing beyond the body.Nature 561 , 239–242 (2018).
    doi:10.1038/s41586-018-0460-0; pmid: 30209365

  2. S. H. Johnson-Frey, The neural bases of complex tool use in
    humans.Trends Cogn. Sci. 8 , 71–78 (2004). doi:10.1016/
    j.tics.2003.12.002; pmid: 15588811

  3. P. M. Greenfield, Language, tools and brain: The ontogeny and
    phylogeny of hierarchically organized sequential behavior.


Behav. Brain Sci. 14 , 531–551 (1991). doi:10.1017/
S0140525X00071235


  1. K. Pastra, Y. Aloimonos, The minimalist grammar of action.
    Philos. Trans. R. Soc. Lond. B Biol. Sci. 367 , 103–117 (2012).
    doi:10.1098/rstb.2011.0123; pmid: 22106430

  2. J. Steele, P. F. Ferrari, L. Fogassi, From action to language:
    Comparative perspectives on primate tool use, gesture and the
    evolution of human language.Philos. Trans. R. Soc. Lond.
    B Biol. Sci. 367 ,4–9 (2012). doi:10.1098/rstb.2011.0295;
    pmid: 22106422

  3. M. Ben-Shachar, T. Hendler, I. Kahn, D. Ben-Bashat,
    Y. Grodzinsky, The neural reality of syntactic transformations:
    Evidence from functional magnetic resonance imaging.
    Psychol. Sci. 14 , 433–440 (2003). doi:10.1111/
    1467-9280.01459; pmid: 12930473

  4. L. W. Barsalou, Grounded cognition.Annu. Rev. Psychol. 59 ,
    617 – 645 (2008). doi:10.1146/annurev.
    psych.59.103006.093639; pmid: 17705682

  5. F. Pulvermüller, L. Fadiga, Active perception: Sensorimotor
    circuits as a cortical basis for language.Nat. Rev. Neurosci. 11 ,
    351 – 360 (2010). doi:10.1038/nrn2811; pmid: 20383203

  6. L. Craighero, L. Fadiga, G. Rizzolatti, C. Umiltà, Action for
    perception: A motor-visual attentional effect.J. Exp. Psychol.
    Hum. Percept. Perform. 25 , 1673–1692 (1999). doi:10.1037/
    0096-1523.25.6.1673; pmid: 10641315

  7. C. Brozzoliet al., Touch perception reveals the dominance of
    spatial over digital representation of numbers.Proc. Natl. Acad.
    Sci. U.S.A. 105 , 5644–5648 (2008). doi:10.1073/
    pnas.0708414105; pmid: 18385382

  8. M. H. Fischer, A. D. Castel, M. D. Dodd, J. Pratt, Perceiving
    numbers causes spatial shifts of attention.Nat. Neurosci. 6 ,
    555 – 556 (2003). doi:10.1038/nn1066; pmid: 12754517

  9. O. Hauk, I. Johnsrude, F. Pulvermüller, Somatotopic
    representation of action words in human motor and premotor
    cortex.Neuron 41 , 301–307 (2004). doi:10.1016/S0896-6273
    (03)00838-9; pmid: 14741110

  10. S. M. Wilson, A. P. Saygin, M. I. Sereno, M. Iacoboni, Listening
    to speech activates motor areas involved in speech production.
    Nat. Neurosci. 7 , 701–702 (2004). doi:10.1038/nn1263;
    pmid: 15184903

  11. M. A. Just, P. A. Carpenter, T. A. Keller, W. F. Eddy,
    K. R. Thulborn, Brain activation modulated by sentence
    comprehension.Science 274 , 114–116 (1996). doi:10.1126/
    science.274.5284.114; pmid: 8810246

  12. M. Makuuchi, J. Bahlmann, A. Anwander, A. D. Friederici,
    Segregating the core computational faculty of human language
    from working memory.Proc. Natl. Acad. Sci. U.S.A. 106 ,
    8362 – 8367 (2009). doi:10.1073/pnas.0810928106;
    pmid: 19416819

  13. A. Santi, Y. Grodzinsky, Working memory and syntax interact in
    Broca’s area.Neuroimage 37 ,8–17 (2007). doi:10.1016/
    j.neuroimage.2007.04.047; pmid: 17560794

  14. P. Fazioet al., Encoding of human action in Broca’s area.
    Brain 132 , 1980–1988 (2009). doi:10.1093/brain/awp118;
    pmid: 19443630

  15. A. C. Royet al., Syntax at hand: Common syntactic structures
    for actions and language.PLOS ONE 8 , e72677 (2013).
    doi:10.1371/journal.pone.0072677; pmid: 23991140

  16. F. Vargha-Khadem, K. Watkins, K. Alcock, P. Fletcher,
    R. Passingham, Praxic and nonverbal cognitive deficits in a
    large family with a genetically transmitted speech and
    language disorder.Proc. Natl. Acad. Sci. U.S.A. 92 , 930– 933
    (1995). doi:10.1073/pnas.92.3.930; pmid: 7846081

  17. F. Pulvermüller, The syntax of action.Trends Cogn. Sci. 18 ,
    219 – 220 (2014). doi:10.1016/j.tics.2014.01.001;
    pmid: 24582824

  18. M. T. Ullman, A neurocognitive perspective on language: The
    declarative/procedural model.Nat. Rev. Neurosci. 2 , 717– 726
    (2001). doi:10.1038/35094573; pmid: 11584309

  19. E. Koechlin, T. Jubault, Broca’s Area and the Hierarchical
    Organization of Human Behavior, Broca’s area and the
    hierarchical organization of human behavior.Neuron 50 ,
    963 – 974 (2006). doi:10.1016/j.neuron.2006.05.017;
    pmid: 16772176

  20. L. Maffongelliet al., Distinct brain signatures of content and
    structure violation during action observation.Neuropsychologia
    75 , 30–39 (2015). doi:10.1016/j.neuropsychologia.2015.05.020;
    pmid: 26004058

  21. M. J. D. Martins, R. Bianco, D. Sammler, A. Villringer, Recursion in
    action: An fMRI study on the generation of new hierarchical levels
    in motor sequences.Hum. Brain Mapp. 40 , 2623–2638 (2019).
    doi:10.1002/hbm.24549; pmid: 30834624

  22. A. C. Roy, M. A. Arbib,The Syntactic Motor System
    (John Benjamins Publishing, 2005).


Thibaultet al.,Science 374 , eabe0874 (2021) 12 November 2021 13 of 14


RESEARCH | RESEARCH ARTICLE

Free download pdf