5. Mucinous Carcinoma (3%)Mucinous carcinoma accounts for about 3% of breast cancers and often presents
in postmenopausal women 75 years and older. A mucin producer, the tumor is
also slow-growing and thus the prognosis is more favorable than in many other
types.6. Tubular Ductal Carcinoma (2%)Tubular ductal carcinoma accounts for about 2% of breast cancers. Because
axillary metastases are uncommon with this histology, prognosis is usually
excellent.7. Inflammatory Carcinoma (2%)Inflammatory carcinoma is a rare (1% to 2%) and aggressive type of breast
cancer that has unique symptoms. The cancer is characterized by diffuse edema
and brawny erythema of the skin, often referred to as peau d'orange (resembling
an orange peel). This is due to malignant cells blocking the lymph channels in
the skin. An associated mass may or may not be present; if there is, it is often a
large area of indiscrete thickening. Inflammatory carcinoma can be confused
with an infection because of its presentation. The disease can spread to other
parts of the body rapidly. Chemotherapy often plays an initial role in controlling
disease progression, but radiation and surgery may also be useful.8. Paget Disease (1%)Paget disease of the breast accounts for 1% of diagnosed breast cancer cases.
Symptoms typically include a scaly, erythematous, pruritic lesion of the nipple.
Paget disease often represents ductal carcinoma in situ of the nipple but may
have an invasive component. Mammography should be performed followed by
a biopsy of the involved skin area.Signs and symptoms
Subjective: nontender nodule
Objective:
- Enlarged axillary nodes • Nipple retraction or elevation
- Skin dimpling • Nipple discharge
- Usually appeal in the upper outer quadrant
Diagnostic tests and methods: Mammography, breast biopsy examination