276 CHAPTER 7
FEEDBACK LOOPS IN TREATMENT: Panic Disorder
Invariably, medication—which changes neurological functioning—stops exerting its
benefi cial effect when the patient stops taking it. The positive changes in neural
communication and brain activity, and the associated changes in thoughts, feelings,
and behaviors do not endure. Eventually, the symptoms of panic disorder return.
For some patients, though, medication is a valuable fi rst step, providing enough
relief from symptoms that they are motivated to obtain CBT, which can change
their reactions (psychological factor) to perceived bodily sensations (neurological
factor). When a patient receives both medication and CBT, however, the medication
should be at a low enough dose that the patient can still feel the sensations that led
to panic in the past (Taylor, 2000). In fact, the dose should be gradually decreased
so that the patient can experience enough anxiety to be increasingly able to make
use of cognitive-behavioral methods. It is the CBT that leads to enduring changes:
Researchers have found that adding medication to CBT doesn’t provide an advan-
tage over CBT alone (de Beurs et al., 1999). This fi nding has led to CBT’s being
recommended even for those who prefer medication (Ellison & McCarter, 2002).
Whether it involves medication or CBT or both, successful treatment will probably
lead the patient, especially if he or she also has agoraphobia, to become more
independent—which in turn can change the person’s relationships, particularly
with their safe people (social factor). These factors and their feedback loops are
summarized in Figure 7.7.
Figure 7.7
7.7 • Feedback Loops in
Treating Panic Disorder
and Agoraphobia
Changes neural
activity
Treatments Targeting
Neurological Factors
Medication: SSRIs,
SNRIs, TCAs,
benzodiazepines
Treatments Targeting
Psychological Factors
CBT: Breathing
retraining, relaxation,
interoceptive
exposure, exposure to
agoraphobia-related
stimuli,
psychoeducation,
cognitive restructuring
Changes thoughts,
feelings, and
behaviors
Decreases shame and
isolation
Increases family
members’ support
Treatments Targeting
Social Factors
Group therapy
Couples or family
therapy
P S
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