310 CHAPTER 7
Key Concepts and Facts About Obsessive-Compulsive Disorder
- OCD is marked by persistent and intrusive preoccupations
and—in most cases—repetitive, compelled behaviors that usu-
ally correspond to the obsessions. Although people with OCD
recognize that their obsessions are irrational, they cannot turn
off the preoccupying thoughts; they feel driven to engage in the
compulsive behaviors, which provide only brief respite from the
obsessions. - Common obsessions include anxiety about contamination, or-
der, losing control, doubts, and possible future need. Common
compulsions include washing, ordering, counting, checking, and
hoarding or collecting. - Neurological factors associated with OCD include disruptions
in the normal activity of the frontal lobes, the thalamus, and
the basal ganglia; the frontal lobes do not turn off activity of
the neural loop among these three brain areas, which may lead
to the persistent obsessions. Lower than normal levels of se-
rotonin also appear to play a role, although this may be more
directly related to some types of OCD than others. Genes ap-
pear to make some people more vulnerable to anxiety disorders
in general—not necessarily to OCD specifi cally.
- Psychological factors that may underlie OCD include negative
reinforcement of the compulsive behavior, which temporarily
relieves the anxiety that arises from the obsession. In addition,
normal preoccupying thoughts may become obsessions when
the thoughts are deemed “unacceptable” and hence require
controlling. In turn, the thoughts lead to anxiety, which is then
relieved by a mental or behavioral ritual. Like people with other
anxiety disorders, people with OCD have cognitive biases re-
lated to their feared stimuli, in this case, regarding the theme of
their obsessions. - Social factors related to OCD include socially induced stress,
which can infl uence the onset and course of the disorder, and
culture, which can influence the particular content of obses-
sions and compulsions.
Figure 7.16
7.16 • Feedback Loops in Treating Obsessive-Compulsive Disorder
Treatments Targeting
Neurological Factors
Medication: SSRIs,
clomipramine (TCA)
Changes neural
activity
Treatments Targeting
Psychological Factors
Family therapy or
consultation
Changes family
dynamic regarding
patient’s compulsive
behaviors
Treatments Targeting
Targeting Psychological Factors
CBT: Exposure with
response prevention,
cognitive restructuring
Changes thoughts,
feelings, and
behaviors