Substance Use Disorders 387
abuse or dependence. The gateway hypothesis is not a blueprint for all users; rather,
it is a way to understand how people who abuse substances come to end up in that
situation. In addition, even when people do come to abuse drugs or be dependent on
them, they do not necessarily go through the specifi ed sequence. In fact, some people
with substance abuse problems had a reverse pathway: They started using harder
drugs before softer ones (George & Moselhy, 2005), for example, using marijuana
before using tobacco (Humfl eet & Haas, 2004).
Factors Associated With Progressing from Entry Drugs to Hard Drugs
Two factors are associated with progressing from using entry drugs to using hard
drugs:
- Age. The younger a person is when he or she starts to use drugs or alcohol, the
more likely he or she will be to abuse drugs later in life—and the less likely to
decrease drug use or stop abusing drugs (D’Amico et al., 2001; Ginzler et al.,
2003; Kandel & Yamaguchi, 1985; McGue & Iacono, 2005; Odgers et al.,
2008; Sung et al., 2004); - Quantity. In general, the more drugs a person uses at the outset, the more likely
he or she is to continue along the road to substance dependence (Bailey, 1992;
D’Amico et al., 2001).
Note that the common liabilities model and the gateway hypothesis may both
be correct, at least in some cases. And, in fact, they may be conceptually related: An
underlying liability may lead some individuals to start experimenting with drugs
earlier, or more intensely, than others. This earlier or more intense use of drugs may
then lead some people with the underlying common liability to shift from entry
drugs to harder drugs.
Substance Abuse as a Category or on a Continuum?
According to DSM-IV-TR, substance abuse and substance dependence
are separate categories, and a habitual drug user is diagnosed with
either substance abuse or substance dependence (or, in theory, does not
meet the criteria for either diagnosis). However, some research suggests
that the abuse/dependence distinction is artifi cial and that a more mean-
ingful way to conceptualize harmful substance use, at least of alcohol,
is on a continuum of severity (Heath et al., 2003; Langenbucher et al.,
2004; Sher, Grekin, & Williams, 2005). According to this view, substance
use, abuse, and dependence vary not qualitatively but rather quantitatively,
with dependence on the extreme end of a continuum. This continuum is
defi ned by the frequency, quantity, and duration of use (see Figure 9.3).
The more frequent the use, the larger the quantity, and the longer the use
has been going on, the more likely the use is to become abuse. And increas-
ing frequency, quantity, or duration of use can push the diagnosis beyond
abuse to dependence.
According to the continuum approach, we would determine whether any of the
Beatles abused or was dependent on Preludin, for instance, based on how much,
how often, and for how long each of them took the stimulant. This approach quan-
tifi es severity in a way that the DSM-IV-TR criteria do not (O’Malley, Johnston, &
Bachman, 1999; H. A. Skinner, 1995).
Comorbidity
As we’ve noted in earlier chapters, many people with psychological disorders
abuse substances, particularly alcohol, marijuana, cocaine, and opiates (Lingford-
Hughes & Nutt, 2000). In a study specifi cally examining the prevalence of comor-
bid disorders among people with substance use disorders, almost half of those with
alcohol abuse or dependence also had another DSM-IV-TR disorder—and almost
three-quarters of those with drug abuse or dependence had another DSM-IV-TR
disorder (Regier et al., 1993). Common comorbid disorders include mood disorders
9.3 • A Continuum of Substance Use, Abuse,
and Dependence Substance use, abuse, and
dependence may be better conceptualized as occurring
on a continuum rather than as discrete categories. Where
an individual’s use falls on the continuum would be
determined by frequency, quantity, and duration.
Figure 9.3
y
g93
Recreational
use
Dependence
(has difficulty
not using the
substance)
Abuse
(use of the
substance creates
problems)