Understanding Psychological Disorders: The Neuropsychosocial Approach 35
Not surprisingly, such complexity leads to many opportunities for the function-
ing of the brain to go awry. The brain is the organ of thinking, feeling, and behavior,
and thus it must play a key role in psychopathology. In the following sections, we
discuss the brain so that you can begin to understand the neurological aspects of
specifi c psychological disorders that we consider later in the book. We start with the
big picture by considering the overall structure of the brain and its organization into
large systems. Then we turn to increasingly more detailed components, considering
how individual brain cells interact within these systems.
A Quick Tour of the Nervous System
Psychopathology involves defi cits in how a person thinks, feels, and behaves.
The brain, of course, is ultimately responsible for all of these functions. Let’s
briefl y consider how different parts of the brain contribute to cognitive and
emotional capacities when the brain is structured and functions normally. In
later chapters, when we need to know more to understand a specifi c psychologi-
cal disorder, we’ll look more closely at specifi c parts of the brain and how they
can malfunction.
The Central Nervous System and the Peripheral Nervous System
The central nervous system (CNS) has two parts: the brain and the spinal cord. The
CNS is the seat of memory and consciousness, as well as perception and voluntary
action (Smith & Kosslyn, 2006). However, the CNS is not the only neurological
foundation of our internal lives. The peripheral nervous system (PNS) also plays an
important role and is of particular interest in the study of psychopathology.
The Autonomic Nervous System
Like the CNS, the PNS is divided into two parts,
in this case the sensory-somatic nervous system and
the autonomic nervous system (see Figure 2.1). The
sensory-somatic nervous system is involved in con-
necting the brain to the world, via both the senses
(inputs) and the muscles (outputs). The autonomic
nervous system (ANS) is probably of greater rele-
vance to psychopathology, in part because it plays a
key role in how we respond to stress (as we’ll discuss
shortly). The ANS controls many involuntary func-
tions, such as those of the heart, digestive tract, and
blood vessels (Goldstein, 2000; Hugdahl, 2001).
The ANS itself has two major components: the sym-
pathetic nervous system and the parasympathetic
nervous system. Thesympathetic nervous system
revs you up so that you can respond to an emer-
gency: It speeds up the heart (providing more blood
and oxygen to the limbs) and dilates the pupils of
the eyes (making you more sensitive to light). The
sympathetic system also slows down functions that
are not essential in an emergency, such as those in-
volved in digestion. The sum result of the sympa-
thetic nervous system’s being activated is called the
fi ght-or-fl ight response, (or the stress response, be-
cause it occurs when people experience stress).
As part of the fight-or-flight response, the
hypothalamic-pituitary-adrenal axis (HPA axis)
manages the production of the hormone cortisol,
which readies the muscles for physical exertion by helping the body release fuel
more effectively. Under chronic stress, a person’s level of cortisol often doesn’t
2.1 • The Nervous System The autonomic nervous
system (ANS) is part of the peripheral nervous system (PNS), and
malfunctioning of the ANS can produce abnormal responses to stress.
Figure 2.1
21 Th N S t hi
g
Spinal cord Brain Sensory-somatic
nervous system
Autonomic
nervous system
Nervous system
Central
nervous system
Peripheral
nervous system
Sympathetic
nervous system
Parasympathetic
nervous system