CALCIUM-DEPENDENT MOLECULES 305
and B (28 – 39) shown in blue; (2) helix B to helix C connector loop (39 – 44)
shown in orange; (3) helices C (45 – 55) and D (65 – 76) shown in green; (4)
antiparallelβ - sheet connector regions shown in cyan (thr26 – thr28, thr62 –
asp64); (5) helices E (77 – 92) and F (102 – 111) shown in magenta; (6) helix F to
helix G connector loop (112 – 117) shown in orange; (7) helices G (118 – 128)
and H (139 – 146) shown in red; antiparallel β - sheet region shown in cyan (99 –
101, 135 – 137). The connector loops between helices in the helix – loop – helix
calcium - binding domains are shown in green. See also Table 6.7 for interhelical
angles.
Figure 6.22 X - ray crystallographic structures of: (A) Ca 2+ - saturated calmodulin, PDB:
1EXR; and (B) apo - calmodulin, PDB: 1QX5. Visualized using CambridgeSoft Chem3D
Ultra 10.0 with notations in ChemDraw Ultra 10.0. (Printed with permission of Cam-
bridgeSoft Corporation.) (See color plate)
helix A (I)helix B (II)helix C (III)helix D (IV)helix E (V)
helix F (VI)helix G (VII)helix H (VIII)helix H (VIII)helix G (VII)helix C (III)helix D (IV)helix E (V) helix F (VI)helix A (I)helix B (II)1EXRAB 1QX5