BIOINORGANIC CHEMISTRY A Short Course Second Edition

Figure 2.22 Zinc - fi nger – DNA interactions for PDB: 1ZAA as described in reference
31 and the text. Visualized using The PyMOL Molecular Graphics System and Chem-
Draw Ultra, version 10.0. (Printed with permission of Delano Scientifi c, LLC and
CambridgeSoft Corporation.)

cys40

cys37

his53 his57

G4

his25

G7

zinc1

zinc2

zinc3

PDB: 1ZAA.

DNA Strand in orange ribbon.

Protein in green cartoon.

gly155

gly190

A

asp171

thr122, pro123

ser207

asn246

leu147

gly227

PDB: 1YCM

Figure 3.18 Secondary structure of matrix metalloproteinase 12 (MMP12): (A) PDB:
1YCM (structure determined using solution NMR).