BIOINORGANIC CHEMISTRY A Short Course Second Edition

(lu) #1
arg644

ser642, back

ser643

arg644, front

isocitrate glu262, back

arg452, front

asn446

his167

cys358, back

asn258, back
his147

cys421, front

cys424, front

asp100

his101

gln72

asp165

ser166, back

iron-sulfur cluster

Figure 7.50 Important amino acid residues surrounding the isocitrate substrate (black
carbon atoms) and the iron – sulfur cluster of aconitase (PDB: 7ACN). Visualized using
The PyMOL Molecular Graphics System and ChemDraw Ultra, version 10.0. (Printed
with permission of Delano Scientifi c, LLC and CambridgeSoft Corporation.)

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