Manual of Clinical Nutrition

HIV Infection and AIDS

Manual of Clinical Nutrition Management III- 52 Copyright © 2013 Compass Group, Inc.

compared to men, women experience greater increases in blood lipid levels with certain medications (1).
When using ritonavir and nelfinavir, men experience more diarrhea, while women experience nausea,
vomiting, and abdominal pain more frequently than men (1). It is important for the clinician to consider these
differences when assessing nutritional status and medication therapies.

Table III- 11 : HIV Medications: Names, Forms, Interactions, and Potential Side Effects (9)
Generic Name (commercial name);
Class of Drug (manufacturer);
Forms (tablets, capsules, oral
solutions, or injections)

Food, Drink, and

Other Interactions

Potential Side Effects

Abacavir (Ziagen);
NRTI (Glaxo SmithKline);
Tablets, oral solution (strawberry-
banana)

Take with or without

food;

Use caution with

alcohol (increases

amount of time a

drug is active in

your body)

Nausea and vomiting, loss of appetite,

abdominal pain, diarrhea, anemia,

pancreatitis, lactic acidosis (rare)

Abacavir/Lamivudine/Zidovudine
(Trizivir);
NRTI^1 combination (Glaxo SmithKline);
Tablets

Take with or without

food

See side effects on drug labels for

Abacavir, Lamivudine, Zidovudine

Amprenavir (Agenerase);
Protease inhibitor (Glaxo SmithKline);
Capsules (contains sorbitol, vitamin E),
oral solution (grape, bubble gum,
peppermint)— contains acesulfame
potassium, saccharin, vitamin E

Take with or without

food;

Do not take with high-

fat meal;

Do not take with a

vitamin E

supplement;

If taking antacids, take

Amprenavir 1 hour

before or after;

Avoid grapefruit juice;

Increase fluid intake

Diarrhea, nausea and vomiting, taste

changes, stomach upset, diabetes,

fatigue, increased cholesterol levels,

increased triglyceride levels, fat

maldistribution, anemia.

Do not take if you have kidney or liver

failure.

Tipranavir (Aptivus);
Protease inhibitor (Boehringer
Ingelheim Pharmaceuticals);
Capsules

Take with a high-fat

meal

Hypertriglyceridemia, hyperglycemia,

fat maldistribution

Atazanavir (Reyataz)
Protease inhibitor (Bristol-Myers
Squibb)
Capsules (contain lactose)

Take with food Nausea, increased indirect bilirubin,
lactic acidosis (rare);
Be careful if you have liver problems,
may require dose change
Darunavir (Prezista)
Protease inhibitor (Tibotec
Therapeutics)
Capsules

Take with or without

food

Nausea, diarrhea, headache, cold-like

symptoms (runny nose and sore

throat)

Delavirdine (Rescriptor);
NNRTI^2 (Agouron);
Tablets (contain lactose);

Take with or without

food;

Do not take with

antacids or

magnesium-

containing

supplements;

May take with acidic

drinks (such as

cranberry juice);

Avoid drinking alcohol

Increased thirst, loss of appetite, dry

mouth, nausea and vomiting, inflamed

stomach, diarrhea, constipation,

passing gas;

Be careful using this drug if you have

liver problems