xixPET Imaging for Determining Response to Chemotherapy ................. 230
Tissue Systems Biology Approach to Personalized
Management of Cancer ......................................................................... 231
Molecular Diagnostics Combined with Cancer Therapeutics................... 232
Aptamers for Combined Diagnosis and Therapeutics of Cancer .......... 232
Combining Diagnosis and Therapy of Metastatic Cancer .................... 233
Detection and Destruction of CTCs with Nanoparticles
and X-Rays ............................................................................................ 234
Monoclonal Antibodies for Combining Diagnosis
with Therapy of Cancer......................................................................... 234
Molecular Profi ling of Cancer .................................................................. 235
Targeted Cancer Therapies ........................................................................ 235
Targeting Glycoproteins on Cell Surface .............................................. 235
Targeting Pathways in Cancer ............................................................... 236
Targeted Personalized Anticancer Medicines in Clinical Use .............. 236
Immunotherapy of Cancer ........................................................................ 236
Functional Antibody-Based Therapies .................................................. 237
Immunotherapy of Dormant Cancer ..................................................... 239
Personalized Cancer Vaccines ................................................................... 240
Antigen-Specifi c Vaccines .................................................................... 240
Tumor-Derived Vaccines....................................................................... 241
Patient-Specifi c Cell-Based Vaccines ................................................... 244
Adoptive Cell Therapy .......................................................................... 247
Personalized Peptide Cancer Vaccines .................................................. 250
Current Status and Future Prospects of Personalized
Cancer Vaccines .................................................................................... 251
Personalized Radiation Therapy ............................................................... 253
Use of Radiation Sensitivity Biomarkers to Personalized
Radiotherapy ......................................................................................... 255
Use of Imaging to Monitor Radioimmunotherapy
of Non- Hodgkin Lymphoma ................................................................. 255
Role of Nanobiotechnology in Personalized Management
of Cancer ................................................................................................... 256
Design of Future Personalized Cancer Therapies ..................................... 257
Personalized Therapy of Cancer Based on Cancer Stem Cells ............. 258
Role of Epigenetics in Development of Personalized
Cancer Therapies................................................................................... 258
Selective Destruction of Cancer Cells While Sparing Normal Cells .... 259
Role of Oncoproteomics in Personalized Therapy of Cancer ................... 261
Cancer Tissue Proteomics ..................................................................... 261
Role of Sequencing in Personalized Therapy of Cancer........................... 262
Pharmacogenomic-Based Chemotherapy ................................................. 264
Whole Genome Technology to Predict Drug Resistance ...................... 264
Anticancer Drug Selection Based on Molecular
Characteristics of Tumor ....................................................................... 264Contents