Textbook of Personalized Medicine - Second Edition [2015]

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covering BRCA1 and BRCA2; mutations in these genes are linked to an increased
risk for breast and ovarian cancer. Both sides quickly claimed victory. According to
the plaintiffs, the Court’s decision would help society “feel more of the impact of the
genomics revolution”, whereas the Biotechnology Industry Organization claimed
that the decision left intact patents on the synthetic transcripts, “the commercially
most important form of DNA used in biotechnology” (Sherkow and Greely 2013 ).


References


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Caulfi eld T, McGuire AL, Cho M, et al. Research ethics recommendations for whole-genome
research: consensus statement. PLoS Biol. 2008;6:e73.
Chandrasekharan S, Cook-Deegan R. Gene patents and personalized medicine – what lies ahead?
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Cohen JC, Boerwinkle E, Mosley Jr TH, Hobbs HH. Sequence variations in PCSK9, low LDL, and
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N Engl J Med. 2008;358:105–7.
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risk perception and worry among patients receiving routine care in a preventive health clinic.
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O f fi t K. Genomic profi les for disease risk: predictive or premature? JAMA. 2008;299:1353–5.
Sherkow JS, Greely HT. The future of gene patents and the implications for medicine. JAMA
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So D, Joly Y. Commercial opportunities and ethical pitfalls in personalized medicine: a Myriad of
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21 Ethical Aspects of Personalized Medicine
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