Adequate dialysis
Adequacy of dialysis is usually determined by the fractional clearance of urea
(Kt/Vurea) which is also used to guide dosage of dialysis. Determinations of daily
urea clearance are derived by the following formula:
Daily total Kt/Vurea = peritoneal Kt/Vurea + renal Kt/Vurea
Where: K=clearance of urea, t=time (min), V=volume of distributionAdequate dialysis is a term employed to describe the effects of a dialysis dose by
returning the patient with renal failure to almost physiologic parameters of kidney
function and keeping him/her asymptomatic. Optimal dialysis is used to describe
the reduction in morbidity and/or mortality with a determined dose of dialysis
keeping in mind the financial burden or excessive workload if the dose is
increased. [52] Both terms are commonly employed in patients with ESRD.
Outcomes of CRRT in children [12]