Table 1. Initiation Doses for Common Opioids
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(^) Table 2. Initiation Doses for Common Sedatives/Anesthetics
Agent Load/prn Infusion Range
(^) Midazolam
0.05 - 0.1 mg/kg^ 0.05 - 0.1 mg/kg/hr^
(^) Lorazepam
0.05 - 0.1 mg/kg^ -----^
(^) Pentobarbital
0.5 - 1 mg/kg^1 - 2 mg/kg/hr^
(^) Chloral hydrate
25 - 100 mg/kg^ ------^
(^) Ketamine
0.5 – 1 mg/kg^1 - 2 mg/kg/hr^
(^) Clonidine 2 – 5 mcg/kg/day (^)
(transdermal patch 100 300 mcg, change q 7 –
days)
(^) Dexmedetomidine
0.3 - 1 mcg/kg^ 0.2 - 0.7 mcg/kg/hr^
(^) Propofol
2 - 3 mg/kg^75 - 250mcg/kg/min^
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Agent^ Load/prn^ Infusion Range^
(^) Fentanyl
1mcg/kg^1 - 5mcg/kg/hr^
(^) Morphine
0.05 - 0.1mg/kg^ 0.05 - 0.1mg/kg/hr^
(^) Hydromorphone 0.015mg/kg (^10) - 15mcg/kg/hr (^)