ECMO-/ECLS

(Marcin) #1

In-house deliveries require transport from labor and delivery (L&D) to the NICU.
This is accomplished in a warm transport Isolette. These isolettes have a ventilator
attached as part of the unit. Pulse oximetry and cardiorespiratory (CR) monitoring are
also part of many units.


MINIMIZING LUNG INJURY



  1. ARDS net Trial: NEJM 2006
    TV of 6 mL/kg of 1BW and Pplat < 30 cm/LH20 decreased all cause 28 day
    mortality.

  2. FACT trial: NEJM
    CVOP= 4 or PAOP= 8, Increased ventilator five days by 0.6 days, decrease
    ICU days. There was a trend to reduced mortality (underpowered). There was an
    increase in the use of vasopressors.

  3. JAMA 2008
    2 groups were randomized to PEEP 5-9 and higher PEEP while keeping Pplat
    (28-30). There were no mortality benefits with higher PEEP.

  4. Late steroid rescue study for ARDs NEJM 2006: 354; 1671. No significant difference
    between steroid vs no steroids regarding mortality.

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