Logistic Regression: A Self-learning Text, Third Edition (Statistics in the Health Sciences)

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RACE, NP, ASCM, and PAR, and for the interaction
effect of PAR.


  1. For the model used in Exercise 16, describe the strat-
    egy you would use to arrive at a final model that
    controls for confounding and interaction.
    The data below are from a hypothetical pair-matched case-
    control study involving five matched pairs, where the only
    matching variable is smoking (SMK). The disease variable
    is called CASE and the exposure variable is called EXP. The
    matched set number is identified by the variable STRA-
    TUM.
    ID STRATUM CASE EXP SMK
    11 110
    21 010
    32 100
    42 010
    53 111
    63 001
    74 110
    84 000
    95 101
    10 5 0 0 1

  2. How many concordant pairs are there where both pair
    members are exposed?

  3. How many concordant pairs are there where both
    members are unexposed?

  4. How many discordant pairs are there where the case
    is exposed and the control is unexposed?

  5. How many discordant pairs are there where case is
    unexposed and the control is exposed?
    The table below summarizes the matched pairs informa-
    tion described in the previous questions.
    notD
    E notE


D


E 12


notE 11


  1. What is the estimated MOR for these data?

  2. What type of matched analysis is being used with this
    table, pooled or unpooled? Explain briefly.
    The table below groups the matched pairs information
    described in Exercises 19–22 into two smoking strata.


422 11. Analysis of Matched Data Using Logistic Regression

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