GREEN CHIRETTA Andrographis paniculata
Acanthaceae
San: Bhunimbah, Kiratatiktah Hin: Kakamegh, Kalpanath Ben: Kalmegh
Mal: Nilaveppu, Kiriyattu Tam: Nilavempu Kan: Kreata
Importance
Kalmegh, the Great or Green Chiretta is a branched annual herb. It is useful in
hyperdipsia, burning sensation, wounds, ulcers, chronic fever, malarial and intermittent
fevers, inflammations, cough, bronchitis, skin diseases, leprosy, pruritis, intestinal worms,
dyspepsia, flatulence, colic, diarrhoea, dysentery, haemorrhoids and vitiated conditions of
pitta (Warrier et al, 1993). It is used to overcome sannipata type of fever, difficulty in
breathing, hemopathy due to the morbidity of kapha and pitta, burning sensation, cough,
oedema, thirst, skin diseases, fever, ulcer and worms. It is also useful in acidity and liver
complaints (Aiyer and Kolammal, 1962). The important preparations using the drug are
Tiktakagheta, Gorocandi gulika, Candanasava, Panchatiktam kasaya, etc. (Sivarajan et al,
1994). A preparation called “Alui” is prepared by mixing powdered cumin (Cuminium
cyminum) and large cardamom (Amomum subulatum) in the juice of this plant and
administered for the treatment of malaria (Thakur et al, 1989). It is also a rich source of
minerals.
Distribution
The plant is distributed throughout the tropics. It is found in the plains of India from
U.P to Assam, M.P., A.P, Tamil Nadu and Kerala, also cultivated in gardens.
Botany
Andrographis paniculata (Burm.f.) Wall ex. Nees belongs to the family
Acanthaceae. It is an erect branched annual herb, 0.3-0.9m in height with quadrangular
branches. Leaves are simple, lanceolate, acute at both ends, glabrous, with 4-6 pairs of main
nerves. Flowers are small, pale but blotched and spotted with brown and purple distant in
lax spreading axillary and terminal racemes or panicles. Calyx-lobes are glandular
pubescent with anthers bearded at the base. Fruits are linear capsules and acute at both ends.
Seeds are numerous, yellowish brown and sub-quadrate (Warrier et al,1993).
Another species of Andrographis is A. echioides (Linn.) Nees. It is found in the
warmer parts of India. The plant is a febrifuge and diuretic. It contains flavone-echiodinin
and its glucoside-echioidin (Husain et al, 1992).
Agrotechnology
The best season of planting Andrographis is May-June. The field is to be ploughed
well, mixed with compost or dried cowdung and seedbeds of length 3m, breadth 1/2m and
15cm height are to be taken at a distance of 3m. The plant is seed propagated. Seeds are to
be soaked in water for 6 hours before sowing. Sowing is to be done at a spacing of 20cm.
Seeds may germinate within 15-20 days. Two weedings, first at one month after planting and
the second at 2 month after planting are to be carried out. Irrigation during summer months is
beneficial. The plant is not attacked by any serious pests or diseases. Flowering commences
from third month onwards. At this stage, plant are to be collected, tied into small bundles and
sun-dried for 4-5 days. Whole plant is the economic part and the yield is about 1.25t dried
plants/ha (Prasad et al, 1997).
Properties and Activity
Leaves contain two bitter substances lactone “andrographolid” and “kalmeghin”. The
ash contains sodium chloride and potassium salts. Plant is very rich in chlorophyte.
Kalmeghin is the active principle that contains 0.6% alkaloid of the crude plant. The plant
contains diterpenoids, andrographolide, 14-deoxy- 11 - oxo-andrographolide, 14-deoxy-
11,12-dihydroandrographolide, 14-deoxy andrographolide and neoandrographolide (Allison
et al, 1968). The roots give flavones-apigenin-7,4-dio-O-methyl ether, 5-hydroxy-7,8,2’,3’-
tetramethoxyflavone, andrographin and panicolin and α-sitosterol (Ali et al, 1972;