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San: Sarpagandha Hin: Chandrabhaga Mal: Sarpagandhi, Amalpori
Tam: Chivan amelpodi Kan: Sutranbhi Tel: Patalagandhi


Introduction


Serpentwood is an erect, evergreen , perennial undershrub whose medicinal use has
been known since 3000 years. Its dried root is the economical part which contains a number
of alkaloids of which reserpine, rescinnamine, deserpidine, ajamalacine, ajmaline,
neoajmalin, serpentine, α-yohimbine are pharmacologically important. The root is a sedative
and is used to control high blood pressure and certain forms of insanity. In Ayurveda it is
also used for the treatment of insomnia, epilepsy, asthma, acute stomach ache and painful
delivery. It is used in snake-bite, insect stings, and mental disorders. It is popular as
"Madman's medicine" among tribals. 'Serpumsil’ tablet for high blood pressure is prepared
from Rauvolfia roots. Reserpine is a potent hypotensive and tranquillizer but its prolonged
usage stimulates prolactine release and causes breast cancer. The juice of the leaves is used
as a remedy for the removal of opacities of the cornea.


Distribution


Rauvolfia serpentina is native to India. Several species of Rauvolfia are observed
growing under varying edaphoclimatic conditions in the humid tropics of India, Nepal,
Burma, Thailand, Bangladesh, Indonesia , Cambodia, Philippines and Sri Lanka. In India, it is
cultivated in the states of Uttar Pradesh, Bihar, Tamil Nadu, Orissa, Kerala, Assam, West
Bengal and Madhya Pradesh (Dutta and Virmani, 1964). Thailand is the chief exporter of
Rauvolfia alkaloids followed by Zaire, Bangladesh, Sri Lanka, Indonesia and Nepal. In India,
it has become an endangered species and hence the Government has prohibited the
exploitation of wild growing plants in forest and its export since 1969.


Botany


Plumier in 1703 assigned the name Rauvolfia to the genus in honour of a German
physcian -Leonhart Rauvolf of Augsburg. The genus Rauvolfia of Apocynaceae family
comprises over 170 species distributed in the tropical and subtropical parts of the world
including 5 species native to India. The common species of the genus Rauvolfia and their
habitat as reported by Trivedi (1995) are given below.
R. serpentina Benth. ex Kurz.(Indian serpentwood) - India ,Bangladesh, Burma, Sri Lanka,
Malaya, Indonesia
R. vomitoria Afz. (African serpentwood) - West Africa, Zaire, Rwanda, Tanzania
R. canescens Linn. syn. R. tetraphylla (American serpentwood) - America, India
R. mombasina - East Africa , Kenya, Mozambique
R. beddomei - Western ghats and hilly tracts of Kerala
R. densiflora - Maymyo, India
R. microcarpa - Thandaung
R. verticillata syn. R. chinensis - Hemsl
R. peguana - Rangoon-Burma hills
R. caffra - Nigeria, Zaire, South Africa
R. riularis - Nmai valley
R. obscura - Nigeria, Zaire
R. serpentina is an erect perennial shrub generally 15-45 cm high, but growing upto
90cm under cultivation. Roots nearly verticle, tapering up to 15 cm thick at the crown and
long giving a serpent-like appearance, occasionally branched or tortuous developing small
fibrous roots. Roots greenish-yellow externally and pale yellow inside, extremely bitter in
taste. Leaves born in whorls of 3-4 elliptic-lanceolate or obovate, pointed. Flowers numerous
borne on terminal or axillary cymose inflorscence. Corolla tubular, 5-lobed, 1-3 cm long,
whitish-pink in colour. Stamens 5, epipetalous. Carpels 2, connate, style filiform with large
bifid stigma. Fruit is a drupe, obliquely ovoid and purplish black in colour at maturity with
stone containing 1-2 ovoid wrinkled seeds. The plant is cross-pollinated, mainly due to the
protogynous flowers (Sulochana ,1959).

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