The Essentials of Biostatistics for Physicians, Nurses, and Clinicians

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The Essentials of Biostatistics for Physicians, Nurses, and Clinicians,
First Edition. Michael R. Chernick.
© 2011 John Wiley & Sons, Inc. Published 2011 by John Wiley & Sons, Inc.


CHAPTER 8


Contingency Tables


Contingency tables are cross - tabulations of one categorical variable


versus another. They are used to test hypotheses about association
between the variables or differences among proportions. We will see
that the chi - square test is an approximate test for association when the
data set is large enough. Large enough means that each cell in the table
is fi lled with a reasonable number of counts (5 as a minimum is a good
rule of thumb).
On the other hand, Fisher ’ s exact test and its generalizations achieve
the exact signifi cance level, but require an added assumption that the
row sums and the column sums are fi xed at their observed levels when
comparing the existing table with other possible arrangement that occur
under the null hypothesis of no association (sometimes referred to as
independence).
The simplest table is the 2 × 2, where each variable can have only
two categories. However, in general, we have the R × C table where R
is the number of categories for the row variable, and C is the number
of categories for the column.

8.1 2 × 2 TABLES AND CHI - SQUARE


For an example of a 2 × 2 table, consider the case: Let us consider
whether or not there is a difference in the preference for western
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