PDR for Herbal Medicines

HERBAL MONOGRAPHS MUSKMALLOW 7 533

Caffeic acid derivatives: verbascoside (acteoside)

Flavonoids (0.5-4.0%): including among others, rutin, dios-

min, quercetin-7-O-glucoside, hesperidine, apigenin-7-O-

glucoside, kempferol-7-O-glucoside

w Invert sugar (11%)

EFFECTS

Mullein alleviates irritation and has an expectorant effect due

to its mucin and saponin content.

INDICATIONS AND USAGE

Approved by Commission E:

• Cough/bronchitis
  Unproven Uses: Mullein is used internally for catarrh of the
  respiratory tract, bladder and kidney conditions, enteritis,
  rheumatism, coughs, flu, intestinal pain caused by colic,
  asthma, cystitis, hemorrhoids, dermatoses, and painful diar-
  rhea. The plant is used externally for earache, ear furuncles,
  eczema of the auditory canal, middle ear infection, inflam-
  matory skin diseases with itch, burns, eczema, weeping
  eczema, nappy dermatitis, insect bites, and itching in the anal
  and genital regions.
  tt PRECAUTIONS AND ADVERSE REACTIONS
  No health hazards or side effects are known in conjunction
  with the proper administration of designated therapeutic
  dosages.
  DOSAGE
  Mode of Administration: Whole, cut, and powdered drug is
  available in the form of teas and other galenic preparations
  for internal and external use.

How Supplied:

Liquid — 250" n^mT, 285 mg/ml - -

Liquid Extract — 1:1

Preparation: To prepare tea, pour boiling water over 1.5 to 2

gm finely cut drug and strain after 10 to 15 minutes (1

teaspoonful is equivalent to 0.5 gm drug).

To make an oil preparation, pour 100 gm of olive oil over a
handful of fresh flowers. Leave the mixture outdoors in the
sun, stirring several times a day, then filter after 3 to 4
£ weeks.

To prepare a tincture, add 20 gm cut drug to 80 gm of 70%

ethanol and leave to draw for 10 days.

Daily Dose: The daily dose is 3 to 4 gm of drug. The tincture

dose is 20 to 30 drops taken several times a day.

Storage: Mullein must be protected from light and particu-

larly from moisture to prevent the drug from changing color

to brown or dark brown due to the iridoid content.

LITERATURE

Grzybek J, Szewczyk A, Verbascum-Arten - Konigskerze oder

Wollblume Portrait einer Arzneipflanze. In: ZPT 17(6):389-398.

1996.

Haslinger E, Schroder H, Sci Pharm 60:202. 1992.

Klimek B, PA 48:51. 1991.

Kraus K, Franz G, DAZ 127:665. 1987.

Seifert K et al., PM 51:409. 1985.

Swiatek L et al., PM 45:153. 1982.

Swiatek L et al., Pharm Weekbl (Sci Ed) 9:246. 1987.

Further information in:

Kern W, List PH, Horhammer L (Hrsg.), Hagers Handbuch der

Pharmazeutischen Praxis, 4. Aufl., Bde. 1-8: Springer Verlag

Berlin, Heidelberg, New York, 1969.

Madaus G, Lehrbuch der Biologischen Arzneimittel, Bde 1-3,

Nachdruck, Georg Olms Verlag Hildesheim 1979.

Roth L, Daunderer M, Kormann K, Giftpflanzen, Pflanzengifte,

4. Aufl., Ecomed Fachverlag Landsberg Lech 1993.
   Steinegger E, Hansel R, Pharmakognosie, 5. Aufl., Springer
   Verlag Heidelberg 1992.
   Teuscher E, Biogene Arzneimittel, 5. Aufl., Wiss. Verlagsges.
   Stuttgart 1997.
   Wichtl M (Hrsg.), Teedrogen, 4. Aufl., Wiss. Verlagsges.
   Stuttgart 1997.

Musa paradisiaca

See Plantain

Muskmallow

Abelmoschus moschatus

DESCRIPTION

Medicinal Parts: The medicinal parts are the seeds of the

plant and the oil extracted from them.

Flower and Fruit: The flowers are solitary and axillary.

They have 5 to 7 pubescent, linear, 1.5 cm long epicalyx

leaves. The sepals are about 3 cm long. The corolla has a

diameter of 7.5 cm. The petals are sulfur yellow with a

crimson spot at the base. The petals are ovate and lightly

pubescent. The fruit is a 5 to 8 cm long capsule, which is

shaped like a pentagonal pyramid and filled with numerous

large seeds. The seeds are kidney-shaped, compressed and

about 3 mm in diameter. They are grayish-brown, with

numerous striations that are concentric around the hilum.