PDR for Herbal Medicines

(Barré) #1
HERBAL MONOGRAPHS STONE ROOT/733

Musette P, Galelli A, Chabre H et al., Urtica dioica agglutinin,
a V beta 8.3-specific superantigen, prevents the development of
the systemic lupus erythematosus-like pathology of MRL lpr/lpr
mice. In: Eur J Immunol 26:1707-1711, 1996.
Nahrstedt A (1993) Pflanzliche Urologica - eine kritische
Ubersicht. Pharm Z 138: 1439-1450.
Noske HD (1994) Die Effektivitat pflanzlicher Prostatamittel am
Beispiel von Brennesselwurzelextrakt. ArzteZ Naturheilverfahren
35 (1): 18-27.
Sabo A et al., Radix Urticae (Urtica dioica): Influence on
erythrocyte deformability and enzymes. In: PM 62, Abstracts of
the 44th Ann Congress of GA, 60. 1996.
Schiebel-Schlosser G, Die Brennessel. In: PTA 8(1):53. 1994.
Schilcher H (1987a) Pflanzliche Diuretika. Urologe [B]27:215-
222: (1987b) Moglichkeiten und Grenzen der Phytotherapie am
Beispiel pflanzlicher Urologika. Urologe [B]27:316-319.
Schilcher H, Boesel R, Effenberger ST Segebrecht S, Neuere
Untersuchungsergebnisse mit aquaretisch, antibakteriell und
prostatotrop wirksamen Arzneipflanzen. In: ZPT 10(3):77. 1989.
Schilcher H, Urtica-Arten - Die Brennessel. In: ZPT 9(5): 160.
1988.
Schmidt K (1983) Die Wirkung eines Radix Urticae-Extrakts
und einzelner Nebenextrakte auf das SHBG des Blutplasmas bei
der benignen Prostatahyperplasie. Fortschr Med 101:713-716.
Schmidt K (1983) Die Wirkung eines Radix Urticae-Extrakts
und einzelner Nebenextrakte auf das SHGB des Blutplasmas bei
der benignen Prostatahyperplasie. Fortschr Med 101:713-716.
Schoettner M, Gansser D & Spiteller G: Lignans from the ropts
of Urtica dioica and meir metabolites bind to human sex
hormone binding globlin (SHBG). In: Planta Med 63:529-532,
1997.
Sokeland J, Albrecht J, Combination of Sabal and Urtica extract
vs. finasteride in benign prostatic hyperplasia (Aiken stages I to
II). Comparison of therapeutic effectiveness in a one year
double-blind study. In: Urologe A 36(4):327-33, July, 1997.
Sonnenschein R (1987) Untersuchung der Wirksamkeit eines
prostatotropen Phytotherapeutikums (Urtica plus) bei benigner
Prostatahyperplasie und Prostatitis - eine prospektive
multizentrische Studie. Urologe [B]27:232-237.
Wagner H et al., Studies on the binding of Urtica dioica
agglutinin (UDA) and other lectins in an in vitro epidermal
growtii factor receptor test. In: Phytomedicine 1:287-290. 1994.
Wagner H, Wilier F, Samtleben R, Boos G (1994) Search for
the antiprostatic principle of stinging nettle (Urtica dioica) roots.
Phytomedicine 1:213-224.
Wilier F, Wagner H, Schecklies E, Urtica-Wurzelextrakte. In:
DAZ 131(24):1217. 1991.
Further information in:
Madaus G, Lehrbuch der Biologischen Arzneimittel, Bde 1-3,
Nachdruck, Georg Olms Verlag Hildesheim 1979.


Schulz R, Hansel R, Rationale Phytotherapie, Springer Verlag
Heidelberg 1996.


Steinegger E, Hansel R, Pharmakognosie, 5. Aufl., Springer
Verlag Heidelberg 1992.
Teuscher E, Biogene Arzneimittel, 5. Aufl., Wiss. Verlagsges.
Stuttgart 1997.
Wichtl M (Hrsg.), Teedrogen, 4. Aufl., Wiss. Verlagsges.
Stuttgart 1997.

Stone Root


Collinsonia canadensis


DESCRIPTION
Medicinal Parts: The medicinal parts of the plant are the
fresh or dried roots and rhizomes.

Flower and Fruit: The flowers are dirty yellow, labiate, with
red venation on the inside in richly blossomed panicles. The
upper lip has an obtuse tip. The side tips of the lower lip are
small and rounded; the middle tips are larger and fringed.
The calyx is acuminate and has 2 stamens. The fruit is a
small globose nutlet.

Leaves, Stem and Root: The plant is a perennial that grows
90 to 120 cm high. The rhizome is grayish-brown, very hard,
fibrous and up to 8 cm long. The shoots are glabrous, often
tinged red, with few side shoots. The bark is very thin. The
leaves are light green above and pale green, glabrous, broad,
cordate or ovate below, becoming narrower and shorter
above.

Characteristics: The smell is strongly aromatic, unpleasant,
and numbing in large amounts. The taste is unpleasantly
bitter.

Habitat: The plant is indigenous to North America from
Canada to the Carolinas in the U.S. It is also found in central
Europe.

Production: Stone Root, the rhizome and root of Collinsonia
canadensis, is gathered and dried in autumn.

Other Names: Hardhack, Horseweed, Heal-All, Knob Grass,
Knob Root, Richweed, Richleaf, Knobweed, Hardback

ACTIONS AND PHARMACOLOGY
COMPOUNDS
Volatile oil: chief components are caryophyllene, germa-
crene D, limonene, alpha- and beta-pinenes

Caffeic acid derivatives: including rosmaric acid

EFFECTS
Stone Root has stomachic, tonic and diuretic effects,
probably due to the presence of the essential oil and rosmaric
acid.
Free download pdf