Food. Used as a flavor ingredient in chewing
gum and other major categories of food pro-
ducts, such as alcoholic and nonalcoholic
beverages, frozen dairy desserts, candy, baked
goods, and gelatins and puddings. Use levels
are usually rather low.
Traditional Medicine. Reportedly used in
treating cancer.^7 Resin used in Peruvian folk-
medicineintreatingasthma,bronchitis,catarrh,
colds, rheumatism, wounds, sores, sprains,
headache, veneral diseases, and fevers.8,9
COMMERCIAL PREPARATIONS
Crude, resinoid, extracts, and tincture. Tinc-
ture is official in N.F.
Regulatory Status. Approved for food use
as a natural flavoring (§172.510). Subject of
a German therapeutic monograph; allowed
in preparations with a mean daily dose of
0.6 g for catarrhs of the respiratory tract
(BLUMENTHAL1).
REFERENCES
See the General References forARCTANDER;BLUMENTHAL1;CLAUS;FEMA;GUENTHER;UPHOF;USD26th;
YOUNGKEN.
- I. Wahlberg et al.,Acta Chem. Scand., 25 ,
3285 (1971).
- K. J. Harkiss and P. A. Linley,J. Pharm.
Pharmacol., 25 (Suppl.), 146P (1973).
- D. L. J. Opdyke,Food Cosmet. Toxicol.,
14 (Suppl.), 689 (1976).
- I. Wahlberg and C. R. Enzell,Acta Chem.
Scand., 25 , 70 (1971).
5. H. D. Friedel and R. Matusch,Helv. Chim.
Acta, 70 , 1616 (1987).
6. K. J. Harkiss, personal communication.
7. T. N. Salam and J. F. Fowler Jr.,J. Am.
Acad. Dermatol., 45 , 377 (2001).
8. J. L. Hartwell,Lloydia, 33 , 97 (1970).
9. J. A. Duke and R. Vasquez,Amazonian
Ethnobotanical Dictionary, CRC Press,
Boca Raton, FL, 1994, p. 121.
BARBERRY
Source: Berberis vulgaris L., Mahonia
aquifolium Nutt. (syn. B. aquifolium
Pursh), or otherBerberisspecies (Family
Berberidaceae).
Common/vernacular names: Barberry, ber-
beris, common barberry, and European bar-
berry (B. Vulgaris); berberis, Oregon grape,
and trailing mahonia (Mahonia aquifolium).
GENERAL DESCRIPTION
Berberis vulgaris is a deciduous spiny
shrub that may reach 5 m in height; native
to Europe, naturalized in eastern North
America.
Berberis aquifoliumis an evergreen spine-
less shrub, 1–2 m high; native to the Rocky
Mountains, extending to British Columbia and
California.
Parts used are the dried rhizome and roots
(B. aquifolium) and barks of stem and root
(B. vulgaris).
CHEMICAL COMPOSITION
Berberisspp.arerich inisoquinolinealkaloids;
those inB. vulgarisinclude berberine, berba-
mine, oxyacanthine, jatrorrhizine, columba-
mine, palmatine, isotetrandine (berbamine
72 Barberry