REFERENCES
See the General References forBAILEY2;FEMA;LUST;ROSENGARTEN;TERRELL;UPHOF.
- J. H. Zwaving et al.,Pharm. Weekbl., 106 ,
182 (1971).
- J. Van Loon,Z. Lebensm. Unters. Forsch.,
153 , 289 (1973).
- S. O. Brown et al.,Phytochemistry, 14 ,
2726 (1975).
- J. B. Harborne and C. A. Williams,
Phytochemistry, 11 , 1741 (1972).
- S. Fejes et al.,J. Ethnopharmacol., 69 , 259
(2000).
CHESTNUT LEAVES
Source: Castanea dentata(Marsh.) Borkh.
(syn.C.americana(Michx.) Raf.) (Family
Fagaceae).
Common/vernacular names:American chest-
nut leaves, chestnut leaves.
GENERAL DESCRIPTION
Deciduous tree with rough bark and glabrous
mature leaves that reach about 25 cm in length
and 5 cm in width; up to about 30 m high;
native to North America. Parts used are the
dried leaves.
Once a dominant hardwood species in
eastern North America, the American chest-
nut has been extensively destroyed by a
fungal disease during recent years caused
by Cryphonectria (Endothia) parasitica
(Murrill) Barr (chestnut disease fungus).^1
Consequently, the leaves used in commerce
are mostly derived from Spanish chestnut
leaves (C. sativa Mill.), a native of the
Mediterranean region, or from otherCasta-
neaspecies.
CHEMICAL COMPOSITION
Contains 8–9% tannins, mucilage, resins, and
others.
PHARMACOLOGY AND BIOLOGICAL
ACTIVITIES
Considered to have tonic and astringent prop-
erties;alsoantitussive,antirheumatic.Offersno
advantageoverotherantitussives(WEISS;WREN).
USES
Food. Used in alcoholic and nonalcoholic
beverages in the form of an extract; reported
use levels are low, less than 0.0075%.
Traditional Medicine. Decoction of leaves
used by the Cherokee Indians in a compound
formula to treat coughs; leaves used by
the Mohegans to treat colds and rheumatism;
leaf infusion used to treat whopping cough
(MOERMAN); infusion of a gargle in pharyngitis;
also as sedative, tonic, and astringent.
COMMERCIAL PREPARATIONS
Crude and extracts. Crude was formerly offi-
cial in N.F. and U.S.P. Strengths (seeglossary)
of extracts are expressed either in weight-
to-weight ratios or, when intended for food
use, in flavor intensities.
Regulatory Status. Leaves approved for food
use as natural flavoring substance (§172.510);
onlyC.dentatais listed.Castaneasativaleaves
are the subject of a German therapeutic mono-
graph; however, use is not recommended since
efficacyisnotwelldocumented(BLUMENTHAL1).
186 Chestnut leaves