- In 1919, he demonstrated by epidemiological and laboratory proof that
commercially canned ripe olives had induced severe and fatal botulism.
The result was that the California olive packers spent several hundred
thousand dollars in studying and revamping their canning methods in
such a way that the danger from this product was eliminated. - In 1920, he described an influenza epidemic in an isolated island
community, clarified the method of spread and the characteristics of
immunity. - In 1922-1923, he helped control a typhus outbreak among Navajo
Indians in New Mexico. - In 1925-1927, he demonstrated methods for eliminating tetanus
following smallpox vaccination. In 1925, he demonstrated that a
number of cases of post-vaccination tetanus were attributable to the
employment of bunion pads as vaccination dressings. Tetanus spores
were found in the glue of such pads. In 1927, he demonstrated on
epidemiological grounds that post vaccination tetanus peculiar to the
United States was always confined to primary vaccinations that were
covered with some sort of shield or dressing strapped to the vaccination
site. Experiments showed that the vaccine intentionally seeded with
tetanus spores permitted the development of tetanus only if the site was
covered by some sort of occlusive dressing strapped to the vaccination
site or if the vaccination was administered in a traumatic fashion.
Elimination of vaccination dressings and discontinuation of the
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