SINUSITIS
Sinusitis is the inflammation of the mucous membranes of the maxillary, frontal,
ethmoid, or sphenoid sinuses. Patients may take systemic or nasal decongestants
to reduce the congestion that frequently accompanies sinusitis. Patients are told
to drink plenty of fluids, to rest, and to take acetaminophen (Tylenol) or ibupro-
fen for discomfort. In some cases, antibiotics are prescribed if the condition is
severe or long lasting and an infection is suspected.
CHAPTER 14 Respiratory Diseases^259
Antihistamine Used to Treat Allergic Rhinitis (continued)
Piperazine Derivative—hydroxyzine PO: 25–100 mg tid/qid
(Atarax, Vistaril) Pregnancy category: C
Protein bound: Unknown
Half-life: 3 hours
Butyrophenone Derivative PO: 60 md bid
(terfenadine (Seldane) Pregnancy category: C
Protein bound: 97%
Half-life: 20 hours
Ethanolamine Derivative—carbinoxamine PO: 5 mL qid or 1 tab qid
and pseudoephedrine (Rondec) Pregnancy category: C
Protein bound: Unknown
Half-life: Unknown
Clemastine fumarate (Tavist) PO: 1.34–2.68 mg bid, tid
Maximum dose 8 mg/d
Pregnancy category: C
Protein bound: Unknown
Half-life: Unknown
Propylamine Derivatives—brompheniramine PO: 4 mg q4 h–6h or
maleate (Bromphen, Dimetane, Histaject, SR: 8 mg q8–12h
Hasahist B, Oraminic II) maximum dose 24 mg/d
IM/IV/SC: 10 mg q8–12h;
max: 40 mg/d
Pregnancy category: C
Protein bound: Unknown
Half-life: 25–36 hours
Triprolidine and pseudoephedrine (Actifed) PO: 2.5 mg q6–8h; max: 10 mg/d
Pregnancy category: B
Protein bound: Unknown
Half-life: 3 hours