Hynes RO: Integrins: Versatility, modulation and signaling in cell
adhesion. Cell69:11–25, 1992.
Jones JP: Concepts of etiology and early pathogenesis of
osteonecrosis, in Schafer M (ed.): Instructional Course
Lectures 43. Rosemont, IL, American Academy of Orthopaedic
Surgeons, 1994, pp 499–512.
Kalfas IH: Principles of bone healing. Neurosurg Focus10:1–4,
2001.
Karladani AH, Granhed H, Karrholm J, et al: The influence of
fracture etiology and type of fracture healing: A review of 104
consecutive tibial shaft fractures. Arch Orthop Trauma Surg
121:325–328, 2001.
Kelsey JL, Hoffman SL: Risk factors for hip fracture. N Engl
J Med316:404–406, 1987.
Kenwright J, Gardner T: Mechanical influences on tibial fracture
healing. Clin Orthop355 (suppl): S179–S190, 1998.
Macey LR, Kana SM, Jingushi S, et al: Defects of early fracture
healing in experimental diabetes. J Bone Joint Surg77A:940–956,
1995.
Mankin HJ: Rickets, osteomalacia and renal osteodystrophy: An
update. Orthop Clin North Am21:81–96, 1990.
McKibbin B: The biology of fracture healing in long bones.
J Bone Joint Surg60B:150–162, 1978.
Mohan S, Baylink DJ: Bone growth factors. Clin Orthop
263:30–48, 1991.
Muschler GF, Lane JM, Dawson EG: The biology of spinal
fusion, in Cotler JM, Cotler HP (eds.): Spinal Fusion: Science
and Technique.Berlin, Springer-Verlag, 1990, pp 9–21.
Perlman MH, Thordarson. Ankle fusion in a high-risk popula-
tion: An assessment of nonunion risk factor. Foot Ankle Int
20:491–496, 1999.
Perren SM: Physical and biological aspects of fracture healing
with special reference to internal fixation. Clin Orthop
232:139–151, 1979.
Prolo DJ: Biology of bone fusion. Clin Neurosurg36:135–146,
1990.
Recker RR: Embryology, anatomy and microstructure of bone, in
Coe FL, Favus MJ (eds.): Disorders of Bone and Mineral
Metabolism. New York, NY, Raven, 1992, pp 219–240.
Reddi AH, Sampath TK: Bone morphogenetic proteins: Potential
role in osteoporosis, in Marcus R, Feldman D, Kelsey J (eds.):
Osteoporosis. San Diego, CA, Academic Press, 1996, pp 281–
287.
Reichel H, Koeffler HP, Norman AW: The role of the vitamin D
endocrine system in health and disease. N Engl J Med
320:980–991, 1989.
Riebel ED, Boden SD, Whitesides TE, et al: The effect of nico-
tine on incorporation of cancellous bone graft in an animal
model. Spine20:1549–1553, 1995.
Steinberg ME, Brighton CT, Corces A, et al: Osteonecrosis of the
femoral head: Results of core decompression and grafting with
and without electrical stimulation. Clin Orthop249:199–208,
1989.
White AA III, Hirsch C: An experimental study of the immediate
load bearing capacity of some commonly used iliac bone
grafts. Acta Orthop Scand42:482–490, 1971.
White AA III, Panjabi MM, Southwick WO: The four biome-
chanical stages of fracture repair. J Bone Joint Surg
59A:188–192, 1977.
Wolff J: The Law of Bone Remodeling. Translated by Maquet P,
Furlong R. Berlin, Springer-Verlag, 1986.
Yasko AW, Lane JM, Fellinger EJ, et al: The healing of segmental
bone defects, induced by recombinant human bone morpho-
genetic protein: A radiographic, histologic and biomechanical
study in rats. J Bone Joint Surg74A:659–670, 1992.
BIBLIOGRAPHY
Dee R: Bone healing, in Dee R, Mango E, Hurst E, (eds.):
Principles of Orthopaedic Practice. New York, NY, McGraw-
Hill, 1988, pp 68–73.
Dee R: Bone healing, in Dee R, Mango E, Hurst E, (eds):
Principles of Orthopaedic Practice. New York, McGraw-Hill,
1988; pp 68–73, 1988.
12 THE PREPARTICIPATION
PHYSICAL EXAMINATION
Robert E Sallis, MD, FAAFP, FACSM
INTRODUCTION
- It is estimated that well over one million physician
hours are consumed annually in examining over six
million youth athletes.
•The cost effectiveness of yearly preparticipation
examinations(PPEs) has been questioned: Risser et al,
looked at 763 adolescent athletes screened and found
only 16 athletes were identified with significant prob-
lems. Two were disqualified and one received treat-
ment prior to participation. The cost of identifying
these three problems was $4,537.00 per problem.
•Various studies show preparticipation evaluations
(PPEs) disqualified only 0.3 to 1.3% of athletes, and
only 3.2 to 13.5% required consultation.
GOALS
- Detect any condition that may limit an athlete’s par-
ticipation. - Detect any condition that may predispose an athlete to
injury or lead to sudden death during competition.
•Meet legal or insurance requirements. (49 of 50 states
require yearly examinations.)
66 SECTION 1 • GENERAL CONSIDERATIONS IN SPORTS MEDICINE