X]VeiZg,/ DISORDERS OF THE ENDOCRINE SYSTEM
&++ W^dad\nd[Y^hZVhZ
Figure 7.11 Overview of the causes of endocrine
disorders.
Figure 7.12 Structure of the pituitary gland, with
the secreted hormones indicated.
Stimulus
Endocrine
gland
Hormone
synthesis
Storage
Release
Hormone
e.g. lung
tumor
Ectopic source
Target cell
Inactivation site
Excretory site
e.g. liver
e.g. kidney
Antibodies
against gland
Biochemical and
physiological effects
Abnormal
stimulus
Defective
synthesis
Defective
interactions with
target cells
Inappropriate
feedback
control
Defective inactivation
and/or excretion
Defective
release
SSSSSS
SS
SSSS
Oxytocin
ADH
Posterior
pituitary gland
Anterior
pituitary gland
Artery
TSH
ACTH
FSH
LH
Prolactin
GH
Stalk