Biology of Disease

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Membrane

To waste

Dialysis

fluid

Air trap

Arterial pressure Venous pressure

Peristaltic pump

Dialysate

pressure

Urea

Creatinine Phosphate

H+

NADPH NADP++ H+

CH 3 CH 2 OH+ O 2

CH 3 CHO + H 2 O

2e-

FMN 2e-

FAD

Cytochrome P-450

reductase Cytochrome P-450

Smooth endoplasmic reticulum membrane

Figure 12.11 A schematic illustrating the

procedure of hemodialysis.

Figure 12.12 The role of P-450 in the

detoxification of ethanol.