Handbook of Hygiene Control in the Food Industry

Table 19.3

Overview of advantages/disadvantages and application examples

of the different biosensor types

Advantages

Disadvantages

Example is given by

Electrochemical

Simple

Low sensitivity (O

2

electrode)

Draisci

et al.

(1998), at-line

High sensitivity (H

O 2

2

electrode) Low selectivity (H

O 2

2

electrode)

O'Connell & Guilbault (2001b), on-line

High selectivity (O

2

electrode)

Thermal

Versatility

Large amount of enzyme

Ramanathan

et al.

(1999), on-line

Robustness

Expensive

Optical

Low cost

Small concentration range

Biacore AB, mostly off-line

Remote sensing

Interference

Very good signal/noise ratio

Piezoelectric

Simple

Low sensitivity

Janshoff & Steinem (2001)

Fast response

Unwanted adsorption (e.g. proteins,

Low cost for readout device

cell compartments)