Infectious Diseases in Critical Care Medicine

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Clinicians confronted with the first victims must put themselves into the mind of the
enemy. Diagnostic, therapeutic, and infection control decisions must be quickly implemented,
and often based upon inadequate data. They should take into account the possibility of a second
pathogen in the same patient or different pathogens in subsequent patients early in the outbreak
before there is an alteration in the initial and usually most stringent isolation precautions.
Epidemiologic, clinical, laboratory, and historical data on the first patients will often be
the key to identifying the pathogen(s), means of distribution, and the culprits responsible.
Again, the terrorists may be among the first and most critically ill patients presenting to the
intensive care unit.


Cannon to right of them, Cannon to left of them, Cannon behind them Volley’d and thunder’d;
Storm’d at with shot and shell, While horse and hero fell, They that had fought so well Came
thro’ the jaws of Death Back from the mouth of Hell, All that was left of them, Left of six
hundred. When can their glory fade? O the wild charge they made! All the world wondered.
Honor the charge they made, Honor the Light Brigade, Noble six hundred.

REFERENCES


The superior man, when resting in safety, does not forget that danger may come. When in a
state of security he does not forget the possibility of ruin. When all is orderly, he does not forget
that disorder may come. Thus his person is not endangered, and his States and all their clans
are preserved.

—Confucius ( :Ko ̆ng Fu ̄zı ̆in Hanyu Pinyin)(551–479 BC), from The
Confucian Analects


  1. Woods JB, ed.USAMRIDD’s Medical Management of Biological Casualties’ Handbook. 6th ed. Fort
    Detrick, Frederick, Maryland:US Army Medical Research Institute of Infectious Diseases; 2005.

  2. Khardori N. Bioterrorism and bioterrorism preparedness: historical perspective and overview. Infect
    Dis Clin North Am 2006; 20:179–211.

  3. Bray DA. IT needs of CDC’s bioterrorism preparedness & response program. Available at: http://
    http://www.naphit.org/global/library/ann_mtg_2003/NAPHIT-bray.ppt. Accessed on July 2, 2008.

  4. Centers for Disease Control and Prevention, US Department of Health and Human Services.
    Emergency preparedness & response. Available at: http//www.bt.cdc.gov/agent/agentlist-category.
    asp. Accessed on July 2, 2008.

  5. Karwa M, Laganathan RS, Kvetan V. Biowarefare agents. In: Hall JB, Schmidt GA, Wood LDH, eds.
    Principles of Critical Care. 3rd ed. New York: McGraw-Hill, 2005:955–972.

  6. Cleri DJ, Ricketti AJ, Porwancher RB, et al. Viral hemorrhagic fevers: current status of endemic
    disease and strategies for control. Infect Dis Clin North Am 2006; 20:359–393.

  7. Pappas G, Panagopoulou P, Christou L, et al. Category B potential bioterrorism agents: bacteria,
    viruses, toxins, and foodborne and waterborne pathogens. Infect Dis Clin North Am 2006; 20:395–421.

  8. Mushtaq A, El-Azizi M, Khardori N. Category C potential bioterrorism agents and emerging
    pathogens. Infect Dis Clin North Am 2006; 20:423–441.

  9. Rabinoweitz P, Gordon Z, Chudnov D, et al. Animals as sentinels of bioterrorism agents. Emerg
    Infect Dis 2006; 12:647–652.

  10. Tucker JB. Historical trends related to bioterrorism: an empirical analysis. Emerg Infect Dis 1999;
    5:498–504.

  11. Cleri DJ, Porwancher RB, Ricketti AJ, et al. Smallpox as a bioterrorist weapon: myth or menace?
    Infect Dis Clin North Am 2006; 20:329–357.

  12. Morse SA, Budowle B. Microbial forensics: application to bioterrorism preparedness and response.
    Infect Dis Clin North Am 2006; 20:455–473.

  13. Siegel JD, Rhinehart E, Jackson M, et al. Guideline for isolation precautions: preventing transmission
    of infectious agents in healthcare settings 2007. Centers for Disease Control and Prevention,
    June 2007. Available at: http://www.cdc.gov/ncidod/dhqp/pdf/isolation2007.pdf. Accessed on
    July 10, 2008.

  14. Centers for Disease Control. Guideline for preventing the transmission ofMycobacterium tuberculosis
    in health-care settings. MMWR Recomm Rep 2005; 54:1–141.

  15. American Institute of Architects. Guidelines for design and construction of hospital and health care
    facilities. In: American Institute of Architects. Washington DC:American Institue of Architects Press;




482 Cleri et al.

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