- Triadafilopoulos G, Hallstone AE. Acute abdomen as the first presentation of pseudomembranous
colitis. Gastroenterology 1991; 101:685–691. - Manabe YC, Vinetz JM, Moore RC, et al.Clostridium difficilecolitis: an efficient clinical approach to
diagnosis. Ann Intern Med 1995; 123:835–840. - Fekety R. Guidelines for the diagnosis and management ofClostridium difficile-associated diarrhea
and colitis. Am J Gastroenterol 1997; 92:739–750. - Zar FA, Bakkanagari SR, Moorthi KMLST, et al. A comparison of vancomycin and metronidazole for
the treatment ofClostridium difficile-associated diarrhea, stratified by disease severity. Clin Infect Dis
2007; 45:302–307. - Bolton RP, Culshaw MA. Faecal metronidazole concentrations during oral and intravenous therapy
for antibiotic associated colitis due toClostridium difficile.Gut 1986; 27:1169–1172.
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