Instant Notes: Analytical Chemistry

304 Section F – Combined techniques

0 2.00 4.00 6.00 8.00 10.00 12.00 14.00 16.00

Time (min)

m/z

18.00 20.00 22.00 24.00 26.00 28.00 30.00

100

50

0

Signal

3.43

5

7.40

8.35

100

50

0

Relative abundance %

100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300

(a)

(b)

Fig. 2. (a) TIC chromatogram of drug sample; (b) mass spectrum of drug impurity.