Differentiation ofPlasmodiumcontinued Clinical Microbiology Review 264
P. FALCIPARUM P. MALARIAE P. OVALE P. VIVAX
Multiple parasites
per cell?
Double chromatin
dots?
Other characteristics
Note: A 5th species, P. knowlesi, now recognized. Can resemble P. malariae or P. falciparum. Differentiate by PCR.
Rare
Rare
Most common. Rarely fatal.
May cause relapses
Yes
Yes
High mortality. Medical
emergency
No
No
Rarely fatal. Band-
shaped trophs
No
No
Least common. Rarely
fatal. May cause relapses
(From Leventhal R, Cheadle RF. Medical
Parasitology: A Self-Instructional Text,
5th ed. Philadelphia: FA Davis; 2002:118.)