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Viral Structure Clinical Microbiology Review 277


TERM EXPLANATION

Virion


Nucleocapsid


Nucleic acid


Capsid


Envelope


Complete virus particle.

Nucleic acid & capsid.

DNA or RNA. Single- or double-stranded. Linear or circular.

Protein coat that encloses genetic material. May be helical (rod-like) or icosahedral (cuboid). Composed of protein
subunits called capsomers. Protects nucleic acid, enables virus to attach to & enter host cell.

Outer membrane surrounding capsid in some viruses. Aids in attachment to host cell. Viruses without called naked
nucleocapsids.
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