Donor Testing Required by AABB
and/or FDA
Immunohematology Review 423
Typing
ABO
Rh (including weak D)
Antibody screen
Syphilis testing
Antibodies to Treponema pallidumor nontreponemal serological test for syphilis, e.g., RPR
Hepatitis testing
HBsAg
Anti-HBc
Anti-HCV
HCV RNA (NAT)
HIV testing
Anti-HIV-1/2
HIV-1 RNA (NAT)
Other infectious disease testing
Anti-HTLV-I/II
West Nile virus RNA (NAT)
Anti–Tryanosoma cruzi(FDA recommends 1-time donor screening)
Test to detect bacterial contamination of platelets
Culture of platelets or FDA-approved rapid test (e.g., Pan Genera Detection [PGD] test)
For autologous donations, complete donor testing required if tf will occur outside collection facility; otherwise only ABO & Rh required.