Blood Components—Plasma and Derivatives Immunohematology Review 429
STORAGE
COMPONENT PREPARATION TEMPERATURE SHELF LIFE INDICATIONS OTHER
Fresh frozen
plasma (FFP)
Cryoprecipitate
Contains all coag factors.
Check for evidence of
thawing & refreezing.
Thawed at 30°–37°C or by
FDA-approved microwave.
Used for hemophilia A &
von Willebrand disease
only if factor VIII concen-
trate or recombinant
factor preparations not
available. Should contain
≥80 IU of factor VIII &
≥150 mg of fibrinogen.
Plasma separated
from WB & frozen
within 8 hr of
collection
Prepared by thaw-
ing FFP at 1°–6°C,
removing plasma,
& refreezing within
1 hr
Frozen: £–18°C.
After thawing:
1 °–6°C
Frozen: £–18°C.
After thawing: RT
Frozen: 12 mo.
After thawing: 24 hr
Frozen: 12 mo.
After thawing: single
units 6 hr, pools 6 hr
if sterile connecting
device used, other-
wise 4 hr
Deficiency of coag
factors
Fibrinogen & factor
XIII deficiencies