DNA Replicationcontinued
Molecular Diagnostics
(MDx) Review 535
Okazaki fragments
Replication fork
Overall direction of replication
DNA
polymerase
Leading strand
Lagging strand
5 ′
3 ′
3 ′
5 ′
5 ′
3 ′^5 ′^3 ′
(From Buckingham L. Molecular Diagnostics: Fundamentals, Methods, and Clinical Applications, 2nd ed.
Philadelphia: FA Davis; 2012:9.)