Blood Collection Tubes for MDx
Molecular Diagnostics
(MDx) Review 544
STOPPER COLOR CONTENT USE
Lavender EDTA Isolation of DNA & detection of viruses. 1 of preferred anticoagulants for
blood & bone marrow.
White K 2 EDTA & gel barrier Isolation of plasma. Gel forms barrier between plasma & cells.
Blue/black Sodium citrate, gel, density Isolation of mononuclear cells. Gel forms barrier between mononuclears
gradient fluid in plasma & RBCs/granulocytes.
Yellow Acid citrate dextrose (ACD) Enhanced recovery of WBCs for several days after collection. 1 of preferred
anticoagulants for blood & bone marrow.
Green Heparin Generally not recommended. Heparin inhibits polymerase; unacceptable
for testing that involves PCR.