Clinical Applications of Molecular
Diagnosiscontinued
Molecular Diagnostics
(MDx) Review 574
DISCIPLINE APPLICATIONS
Oncology
Other
Dx of cancer, e.g., breast, bladder, lung, colon. KRASmutation in colon cancer predicts lack of response to
certain therapies.
Paternity testing, forensics (DNA fingerprinting), pharmacogenomics (“personalized medicine,” selection of
optimal drug therapy based on patient’s genotype), fetomaternal medicine (circulating DNA & RNA)