Facts on File Encyclopedia of Health and Medicine

156 Drugs

This Drug In Combination with This Drug or Food Consequence of Interaction

beta blockers (acebutolol, oral antidiabetes medications decreases effectiveness of oral antidiabetes
atenolol, betaxolol, medications
bisoprolol, carteolol, masks presence of HYPOGLYCEMIA
carvedilol, esmolol,
labetalol, metoprolol, H2 blockers reduces liver’s ability to metabolize beta blocker,
nadolol, penbutolol, allowing potentially toxic levels to accumulate in
pindolol, propranolol, the blood circulation
sotalol, timolol)
MAOI antidepressants increases MAOI level; high risk for toxicity

cigarette smoking reduces effectiveness of beta blocker

H 2 ANTAGONIST(BLOCKER) antifungal medications reduces absorption and effectiveness of antifungal
MEDICATIONS(cimetidine, medications
famotidine, ranitidine,
nizatidine) oral antidiabetes medications increases effectiveness of antidiabetes medications,
INSULIN raising risk for hypoglycemia

beta blockers increases effectiveness of beta blockers, raising

risk for bradycardia and HYPOTENSION

tricyclic antidepressants (amitriptyline, increases antidepressant level in blood circulation,

desipramine, imipramine, nortriptyline) raising risk for serotonin syndrome

metronidazole (Flagyl) alcohol of any kind (including in action similar to that of disulfiram (antabuse)
medications such as cold and flu products)

lithium lithium toxicity

anticoagulant and antiplatelet medications further decreases clotting response, raising the risk

for bleeding

monoamine oxidase beta blockers sudden, rapid, and very high surge inBLOOD
inhibitor (MAOI) foods high in tyramine (beer, red wine, PRESSURE(potentially fatal)
ANTIDEPRESSANT processed cheeses, smoked meats,
MEDICATIONS avocados, bananas, raisins, cured foods)
(isocarboxazid, phenelzine, GINSENG
selegiline, tranylcypromine) CAFFEINEin beverages or medications