Facts on File Encyclopedia of Health and Medicine

(Jeff_L) #1

396 Cancer


Tumor Marker Corresponding Cancer Reliability


CA-72-4 OVARIAN CANCER; STOMACH CANCER; PANCREATIC unreliable for diagnosis
CANCER; COLORECTAL CANCER


CA-125 ovarian cancer unreliable for diagnosis
may be elevated in women who have
previously had cancer and are currently
cancer free
elevated in endometriosis and benign
OVARIAN CYST


CA-5-3 breast cancer unreliable for diagnosis in early stages;
moderate for diagnosis in metastatic
disease
effective for recurrence
elevation possible in women who do not
have cancer


CA-9-9 pancreatic cancer moderately reliable for diagnosis


CALCITONIN medullary THYROID CANCER effective for diagnosis


CARCINOEMBRYONIC ANTIGEN colorectal cancer; LUNG CANCER; breast cancer unreliable for diagnosis
(CEA) effective for recurrence
elevated in numerous noncancerous
health conditions
elevated in people who smoke


chromogranin A neuroendocrine cancers moderate for diagnosis


HER-2/neu breast cancer unreliable for diagnosis
moderate for monitoring treatment


human chorionic gestational trophoblastic neoplasia (GTN); moderate for diagnosis
gonadotropin (hCG) TESTICULAR CANCER; ovarian cancer effective for monitoring treatment


M-protein multiple myeloma effective for diagnosis
effective for monitoring treatment


NEURON-specific enolase (NSE) small-cell lung cancer (SCLC) modest for diagnosis
moderate for monitoring treatment


PROSTATE-SPECIFIC ANTIGEN(PSA) prostate cancer effective for diagnosis
effective for monitoring treatment
elevated in BENIGN PROSTATIC HYPERPLASIA
(BPH)

Free download pdf