Methandriol
Pronunciation:meth-AN-dree-ol
Chemical Abstracts Service Registry Number:521-10-8
Formal Names:Andris, Arbolic, Crestabolic, Drive, Durandrol, Filibol Forte, Geld-
abol, Hybolin, Methylandrostendiol, Methylandrostenediol, Novandrol, Spec-
triol
Type:Anabolic steroid.Seepage 24
Federal Schedule Listing:Schedule III (DEA no. 4000)
USA Availability:Prescription
Uses.Although the substance is banned from sports, some bodybuilders
and other athletes use it. A rat study found augmented muscle protein among
animals receiving the drug. Researchers have noted that chickens gain more
weight when getting methandriol. Other researchers, however, found no
weight alteration after giving the drug to mares daily for 18 months. The
compound has been tested as a treatment for excessive menstrual bleeding,
but results left investigators rather unimpressed.
Drawbacks.Methandriol can masculinize women’s body signs and behav-
ior, though to a lesser degree than many drugs of this type. Indeed, when
tested on horses, no change was seen in mares’ conduct. Nonetheless,
women’s voices can deepen, and facial hair can appear—effects that may be
permanent. Among bodybuilders there is a claim that the drug feminizes
men’s body signs and behavior. Boys and girls receiving the drug may un-
dergo premature sexual maturity and stop growing in height. Reduced fertility
may occur in men. Unwanted effects can include acne, hair loss, and tissue
swelling due to fluid retention. Researchers noted development of high blood
pressure in rats that steadily dosed on methandriol for several weeks. The
drug is not recommended for persons with high blood pressure, heart trouble,
or prostate disorder. Methandriol is suspected of causing liver damage.
Abuse factors.Not enough scientific information to report on tolerance, de-
pendence, withdrawal, or addiction.
Drug interactions.Not enough scientific information to report.
Cancer.Not enough scientific information to report.
Pregnancy.Pregnant women are supposed to avoid methandriol. Bisexual
fetal development in rats has been attributed to the drug. Other research has